Detection and analysis of photothermal signal generated in capillary channel flow

Satoshi Hirashima, Hitoshi Katae, Akira Harata

    研究成果: ジャーナルへの寄稿学術誌査読

    1 被引用数 (Scopus)


    A photothermal signal from a liquid sample in a capillary channel flow is detected and analyzed to optimize experimental conditions of microfluidic devices used for separation. A theoretical model for photoinduced temperature increase and photothermal signal intensity generated by intensity-modulated cw excitation beams at a crossed-beam configuration is proposed. Four experimental parameters (probe beam offset, excitation beam chopping frequency, linear flow velocity, and excitation beam size) and physical properties of solvent mainly dominate the signal. The model well explains the photothermal signal obtained experimentally under low velocity and high chopping frequency conditions. The obtained results make it possible to optimize the experimental conditions for the highly sensitive detection of chemicals under flow conditions.

    ジャーナルJapanese journal of applied physics
    7 PART 2
    出版ステータス出版済み - 7月 2009

    !!!All Science Journal Classification (ASJC) codes

    • 工学(全般)
    • 物理学および天文学(全般)


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