@article{8000c9e68b5044d5b707965597c73bdc,
title = "Detection and structural analysis of pyrimidine-derived radicals generated on DNA using a profluorescent nitroxide probe",
abstract = "The oxidative damage of DNA is associated with aging and the development of various diseases. Although nucleoside-derived radicals play an important role in DNA oxidation, their analysis methods are limited. Herein, we propose a fluorometric detection and structural analysis of radicals on the surface of oxidatively damaged DNA using a profluorescent nitroxide probe combined with liquid chromatography-fluorometry and high-resolution tandem mass spectrometry.",
author = "Kosho Yamauchi and Yuta Matsuoka and Masatomo Takahashi and Yoshihiro Izumi and Hideto Naka and Yosuke Taniguchi and Kazuaki Kawai and Takeshi Bamba and Yamada, {Ken Ichi}",
note = "Funding Information: This work was partially supported by the AMED-CREST grant (JP21gm0910013 to K. Y.), and the JSPS KAKENHI grants (18K14884 to Y. M.; 17H03977, 18K19405, and 20H00493 to K. Y.; 17H06304 to Y. I. and T. B.; and 17H06299 to T. B.), Japan. This work was also supported by the Platform Project for Supporting Drug Discovery and Life Science Research from AMED. We appreciate technical support provided by the Research Support Center of the Graduate School of Medical Sciences, Kyushu University. Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2021.",
year = "2022",
month = jan,
day = "4",
doi = "10.1039/d1cc04998d",
language = "English",
volume = "58",
pages = "56--59",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "1",
}