Detection of a diabetic sural nerve from the magnetic field after electric stimulation

Takehito Hayami, Keiji Iramina, Akira Hyodo, Xian Chen, Kenji Sunagawa

研究成果: Contribution to journalArticle査読

抄録

In this study, we proposed a new diagnostic technique for diabetic neuropathy using biomagnetic measurement. Peripheral neuropathy is one of the most common complications of diabetes. To examine the injury, the skin potential around the nerve is often measured after electric stimulation. However, measuring the magnetic field may reveal precise condition of the injury. To evaluate the effect of measuring the magnetic field, a simulation study was performed. A diabetic sural nerve was simulated as a bundle of myelinated nerve fibers. Each fiber was modeled as an electric cable of Ranvier's nodes. Anatomical data were used to determine the number of nerve fibers and distribution of nerve fiber diameters. The electric potential and the magnetic field on the skin after electric stimulation were computed to the boundary element method. Biphasic time courses were obtained as the electric potential and the magnetic flux density at measurement points. In diabetic nerves, the longer interpeak latency of the electric potential wave and the shorter interpeak latency of the magnetic flux wave were obtained. Measuring both the electric potential and the magnetic flux density seemed to provide a noninvasive and objective marker for diabetic neuropathy.

本文言語英語
論文番号07B315
ジャーナルJournal of Applied Physics
105
7
DOI
出版ステータス出版済み - 2009

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)

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