Detection of Antibodies to Leptospiral Genus-Specific Antigen in Human and Animal Sera by Indirect Hemagglutination Test with a Partially Purified Genus-Specific Protein Antigen

Noritsugu Sakamoto, Ryo Yanagawa, Etsuro Ono, Hiroshi Kida, Mamoru Mori, Yoshiko Arimitsu, Kiyoto Akama, Jun Yasuda, Kimehiko Too

研究成果: Contribution to journalArticle査読

4 被引用数 (Scopus)

抄録

Antibodies against leptospiral genus-specific antigen were detected in the sera from clinically diagnosed human leptospirosis and suspected animal leptospirosis by indirect hemagglutination (IHA) test with a partially purified genus-specific protein antigen (GP-Ag). The reaction was positive in the infected humans and animals irrespective of the leptospiral serovars. No significant correlation was found between IHA titer against GP-Ag and microscopic agglutination (MA) titer. IHA titer did not always develop in parallel with MA titers. Sera obtained from healthy individuals were negative in both IHA and MA tests.

本文言語英語
ページ(範囲)548-556
ページ数9
ジャーナルZentralblatt fur Bakteriologie Mikrobiologie und Hygiene - Abt. 1 Orig. A
259
4
DOI
出版ステータス出版済み - 1985
外部発表はい

All Science Journal Classification (ASJC) codes

  • 免疫学

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