Development and characterization of porous calcium phosphate cement using α-tricalcium phosphate bead

Pham Trung Kien, Tsuru Kanji, Kunio Ishikawa

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

1 被引用数 (Scopus)

抄録

Interconnected set porous-calcium phosphate cement (set porous-CPC), which has fully interconnected pores could be an ideal bone substitute. In this study, set porous- CPC consisting of α-tricalcium phosphate (α-TCP) beads and acidic calcium phosphate solution was developed and its basic setting reaction was studied. When α-TCP beads were exposed to the acidic calcium phosphate solution, brushite (CaHPO4 ·2H2O) was formed on the surface of the α-TCP beads. The formed brushite crystals interlocked with each other, resulting in a setting reaction of α-TCP microspheres within 10 min at 37°C. As a result of this setting reaction, a fullyinterconnected calcium phosphate macroporous structure was obtained. The set porous-CPC were immersed into simulated body fluid (SBF) at 37oC for different immersion time, The result clearly showed that brushite surface layer transformed to apatite layer after 3 days immersion into SBF solution by dissolution-precipitation reaction. Since apatite layer show excellent tissue response, the set porous-CPC would be a promising biomaterial used as artificial bone substitutes, and as the scaffold for tissue engineering.

本文言語英語
ホスト出版物のタイトル5th International Conference on Biomedical Engineering in Vietnam
編集者Vo Van Toi, Tran Ha Lien Phuong
出版社Springer Verlag
ページ507-510
ページ数4
ISBN(電子版)9783319117751
DOI
出版ステータス出版済み - 1 1 2015
イベント5th International Conference on the Development of Biomedical Engineering, 2014 - Ho Chi Minh City, ベトナム
継続期間: 6 16 20146 18 2014

出版物シリーズ

名前IFMBE Proceedings
46
ISSN(印刷版)1680-0737

その他

その他5th International Conference on the Development of Biomedical Engineering, 2014
Countryベトナム
CityHo Chi Minh City
Period6/16/146/18/14

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Biomedical Engineering

フィンガープリント 「Development and characterization of porous calcium phosphate cement using α-tricalcium phosphate bead」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル