Development of a uniaxial mechanical loading device to evaluate osteogenic differentiation of stem cells seeded on a scaffold material

Masakazu Yamada, Takahisa Anada, Taisuke Masuda, Teruko Takano-Yamamoto, Osamu Suzuki

研究成果: 著書/レポートタイプへの貢献会議での発言

抄録

The present study was designed to investigate the effect of the uniaxial mechanical strain on the proliferation and differentiation of mouse mesenchymal stem D1 cells seeded into the octacalcium phosphate (OCP)/ Gelatin (Gel) composite in vitro. The mechanical stimulation with a uniaxial loading device was analyzed by finite element analysis in order to elucidate quantitatively the effect of the strain on D1 cells seeded into the OCP/Gel composite. The results suggest that osteoblastic differentiation of D1 cells is suppressed by overloading of the compressive strain, but promoted if suitable mechanical stress is provided.

元の言語英語
ホスト出版物のタイトル2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015
出版者Institute of Electrical and Electronics Engineers Inc.
ISBN(電子版)9781479966783
DOI
出版物ステータス出版済み - 3 21 2016
外部発表Yes
イベントInternational Symposium on Micro-NanoMechatronics and Human Science, MHS 2015 - Nagoya, 日本
継続期間: 11 23 201511 25 2015

その他

その他International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015
日本
Nagoya
期間11/23/1511/25/15

Fingerprint

Gelatin
Stem cells
Scaffolds
Stem Cells
Equipment and Supplies
Finite Element Analysis
Mechanical Stress
Phosphates
Mesenchymal Stromal Cells
proliferation
Cell Differentiation
Composite materials
Finite element method
octacalcium phosphate
In Vitro Techniques

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Electrical and Electronic Engineering
  • Biotechnology
  • Education

これを引用

Yamada, M., Anada, T., Masuda, T., Takano-Yamamoto, T., & Suzuki, O. (2016). Development of a uniaxial mechanical loading device to evaluate osteogenic differentiation of stem cells seeded on a scaffold material. : 2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015 [7438233] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MHS.2015.7438233

Development of a uniaxial mechanical loading device to evaluate osteogenic differentiation of stem cells seeded on a scaffold material. / Yamada, Masakazu; Anada, Takahisa; Masuda, Taisuke; Takano-Yamamoto, Teruko; Suzuki, Osamu.

2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015. Institute of Electrical and Electronics Engineers Inc., 2016. 7438233.

研究成果: 著書/レポートタイプへの貢献会議での発言

Yamada, M, Anada, T, Masuda, T, Takano-Yamamoto, T & Suzuki, O 2016, Development of a uniaxial mechanical loading device to evaluate osteogenic differentiation of stem cells seeded on a scaffold material. : 2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015., 7438233, Institute of Electrical and Electronics Engineers Inc., International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015, Nagoya, 日本, 11/23/15. https://doi.org/10.1109/MHS.2015.7438233
Yamada M, Anada T, Masuda T, Takano-Yamamoto T, Suzuki O. Development of a uniaxial mechanical loading device to evaluate osteogenic differentiation of stem cells seeded on a scaffold material. : 2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015. Institute of Electrical and Electronics Engineers Inc. 2016. 7438233 https://doi.org/10.1109/MHS.2015.7438233
Yamada, Masakazu ; Anada, Takahisa ; Masuda, Taisuke ; Takano-Yamamoto, Teruko ; Suzuki, Osamu. / Development of a uniaxial mechanical loading device to evaluate osteogenic differentiation of stem cells seeded on a scaffold material. 2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015. Institute of Electrical and Electronics Engineers Inc., 2016.
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AU - Suzuki, Osamu

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