Development of an analytical pipeline for optimizing substrate feeding and eliminating metabolic bottlenecks

Yuki Kuriya, Shigemitsu Tanaka, Genta Kobayashi, Taizo Hanai, Masahiro Okamoto

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

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Attempts were made to design and develop an analytical pipeline for identifying ways ofincreasing the production of a target metabolite that combine an optimized substrate-feedingschedule with a strategy for identifying and eliminating bottlenecks in metabolic pathways. Asa case study, the proposed analytical pipeline was applied to acetone-butanol-ethanolfermentation by Clostridium bacteria, a process that has attracted considerable attention as ametabolic system capable of producing butanol, a possible biofuel.

元の言語英語
ページ(範囲)1-23
ページ数23
ジャーナルChem-Bio Informatics Journal
11
発行部数1
DOI
出版物ステータス出版済み - 1 1 2011

    フィンガープリント

All Science Journal Classification (ASJC) codes

  • Biochemistry

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