Development of Calcium Phosphate Cement for Rapid Crystallization to Apatite

Masayuki Kon, Youji Miyamoto, Kenzo Asaoka, Kunio Ishikawa, Hae Hyoung Lee

研究成果: Contribution to journalArticle査読

28 被引用数 (Scopus)


The purpose of this study was to develop an α-tricalcium phosphate (α-TCP) cement which transforms to hydroxyapatite (HAP) in a relatively short period. We used calcium and phosphate solutions as the liquid phase for the α-TCP cement. The α-TCP powder was first mixed with CaCl2 solution, and then mixed with Na2HPO4 or Na2HPO4, solution for a total powder liquid ratio of 1.8. The setting time became shorter with the increase in the concentration of calcium and phosphate solutions, reaching 5 min, whereas the setting time was longer than 30 min when distilled water was used as the liquid phase. X-ray diffraction analysis revealed that the cement was mostly transformed to HAP within 24 h when kept in an incubator. We concluded that α-TCP should be mixed with calcium and phosphate solutions since this results in a moderate setting time and fast transformation to HAP even if the method of mixing becomes a little complex.

ジャーナルdental materials journal
出版ステータス出版済み - 1998

All Science Journal Classification (ASJC) codes

  • セラミックおよび複合材料
  • 歯科学(全般)


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