Development of drug carriers for therapy of arterioscleosis

Kenjiro Ikuta, Takeshi Mori, Takuro Niidome, Hiroaki Shimokawa, Yoshiki Katayama

研究成果: 会議への寄与タイプ論文

抄録

The vascular endothelium dysfunction often leads to a cardiovascular disease such as arteriosclerosis. Therefore, detection and evaluation of vascular endothelium disorder in early stage would be very important for the effective diagnosis and therapy. We found that the structural analogues of Evans Blue adsorb to a vascular endothelium denuded region. Thus, we synthesized a polymeric drug carrier which consisted of amphipathic polymer and sensing unit (Evans Blue analogue) and evaluated the characteristics of the polymeric carriers. And then a extracted porcine aorta which was removed endothelial cell in left half area was treated with the micelle solution to evaluate a targeting ability of the micelle.

元の言語英語
ページ5459-5460
ページ数2
出版物ステータス出版済み - 12 1 2006
イベント55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, 日本
継続期間: 9 20 20069 22 2006

その他

その他55th Society of Polymer Science Japan Symposium on Macromolecules
日本
Toyama
期間9/20/069/22/06

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Micelles
Endothelial cells
Polymers

All Science Journal Classification (ASJC) codes

  • Engineering(all)

これを引用

Ikuta, K., Mori, T., Niidome, T., Shimokawa, H., & Katayama, Y. (2006). Development of drug carriers for therapy of arterioscleosis. 5459-5460. 論文発表場所 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, 日本.

Development of drug carriers for therapy of arterioscleosis. / Ikuta, Kenjiro; Mori, Takeshi; Niidome, Takuro; Shimokawa, Hiroaki; Katayama, Yoshiki.

2006. 5459-5460 論文発表場所 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, 日本.

研究成果: 会議への寄与タイプ論文

Ikuta, K, Mori, T, Niidome, T, Shimokawa, H & Katayama, Y 2006, 'Development of drug carriers for therapy of arterioscleosis', 論文発表場所 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, 日本, 9/20/06 - 9/22/06 pp. 5459-5460.
Ikuta K, Mori T, Niidome T, Shimokawa H, Katayama Y. Development of drug carriers for therapy of arterioscleosis. 2006. 論文発表場所 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, 日本.
Ikuta, Kenjiro ; Mori, Takeshi ; Niidome, Takuro ; Shimokawa, Hiroaki ; Katayama, Yoshiki. / Development of drug carriers for therapy of arterioscleosis. 論文発表場所 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, 日本.2 p.
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