Development of gastric cancer with special reference to growth and DNA content. Slow and rapid growing types

D. Korenaga, A. Watanabe, H. Anai, Y. Maehara, K. Sugimachi

研究成果: Contribution to journalArticle査読

5 被引用数 (Scopus)

抄録

We treated two patients with gastric cancer for whom surgery was delayed and the natural course of the tumour could be observed pre and postoperatively. A 70-year -old man with a well differentiated adenocarcinoma in the upper portion of the stomach underwent resection 6 years after the clinical diagnosis. Despite extension upwards towards the lower esophagus during a 6-year period, the tumour could be resected. In a poorly differentiated adenocarcinoma in the lower third of the stomach in a 40-year-old woman, the primary lesion was not distinct on the upper GI series done 6 months before, while at the time of laparotomy, disseminating metastases and pancreas invasion made it impossible to resect the stomach together with the tumor. The tumor in the man had a low DNA ploidy, while the lesion in the woman was characterized by a high ploidy. These finding show the distinct difference in the biological behavior of the tumor in these two patients. The possible correlation between DNA content with speed of growth warrants further attention.

本文言語英語
ページ(範囲)463-467
ページ数5
ジャーナルEuropean Journal of Surgical Oncology
19
5
出版ステータス出版済み - 1 1 1993

All Science Journal Classification (ASJC) codes

  • 外科
  • 腫瘍学

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