Development of nanoparticles sizing method based on fluorescence polarization

Yuki Ishizaki, Terutake Hayashi, Masaki Michihata, Yasuhiro Takaya

研究成果: Contribution to conferencePaper

抄録

We suggest a novel nanoparticle sizing method based on fluorescence polarization analysis. Particle size evaluation can be achieved by measuring the rotational diffusion coefficient, which is sensitive to the particle size. We develop a rotational diffusion coefficient measurement system and a fluorescent probe, which is labelled to particle. In order to verify the feasibility of the proposed method, fundamental experiments are performed. We measure the rotational diffusion coefficients of gold nanoparticles, whose diameters are 5 nm, 10 nm and 15 nm, using the developed system. The measured rotational diffusion coefficients decrease with increasing the particle size. It indicates that nanoparticle size, which is below 15 nm, can be measured with at least 5 nm resolution.

本文言語英語
ページ319-322
ページ数4
出版ステータス出版済み - 2013
イベント11th IMEKO TC14 International Symposium on Measurement and Quality Control, ISMQC 2013 - Cracow and Kielce, ポーランド
継続期間: 9 11 20139 13 2013

その他

その他11th IMEKO TC14 International Symposium on Measurement and Quality Control, ISMQC 2013
Countryポーランド
CityCracow and Kielce
Period9/11/139/13/13

All Science Journal Classification (ASJC) codes

  • Safety, Risk, Reliability and Quality

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