Development of novel collagen scaffolds with different bioceramic particles for bone tissue engineering

Takaaki Arahira, Mitsugu Todo

研究成果: Contribution to journalArticle査読

1 被引用数 (Scopus)

抄録

Porous scaffolds comprising natural polymers and bioceramic particles have recently been used in tissue engineering. Collagen is one such natural polymer providing favorable biological conditions; for example, it stimulates the generation and differentiation of cells as an extracellular matrix. α-Tricalcium phosphate (α-TCP) and β-tricalcium phosphate (β-TCP) have also been widely used in bone tissue engineering owing to their favorable osteoconductivity, cellular adhesion, accelerated differentiation, and mechanical properties. In the present study, collagen scaffolds with different bioceramic particles were successfully fabricated by varying the ratio of α-TCP and β-TCP particles. Our results indicate that material properties, such as compressive modulus, swelling behavior, and porosity, can be controlled by varying the ratio of α-TCP and β-TCP particles.

本文言語英語
ページ(範囲)30-32
ページ数3
ジャーナルComposites Communications
16
DOI
出版ステータス出版済み - 12 2019

All Science Journal Classification (ASJC) codes

  • セラミックおよび複合材料
  • 材料力学
  • ポリマーおよびプラスチック
  • 材料化学

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