Development of self-setting calcium hydroxide preparation using dicalcium phosphate anhydrous and sodium hydrogen phosphate aqueous solution

Mariko Nakamura, Kunio Ishikawa, Yasuhiro Yoshida, Kazuomi Suzuki, Toshio Yamamoto

研究成果: Contribution to journalArticle査読

1 被引用数 (Scopus)

抄録

Although a calcium hydroxide preparation is widely used in dental clinics as a base liner and a root canal filling material, its very high basicity causes necrosis of the dental pulp and it does not set. In this study, we evaluated the feasibility of developing a calcium hydroxide preparation that has a good setting ability and a moderate basicity. The calcium hydroxide preparation examined showed a good setting ability and formed an apatitic mineral upon setting when dicalcium phosphate anhydrous (DCPA) powder was added and mixed with sodium hydrogen phosphate aqueous solution. Setting mechanism had a close relationship with apatite formation. As a result of the addition of DCPA, that is, acidic calcium phosphate, the calcium hydroxide preparation showed a relatively mild basicity when compared with the DCPA-free calcium hydroxide preparation. An animal study demonstrated that a calcium hydroxide preparation containing DCPA causes less inflammatory response at the initial stage and elicits faster secondary dentin formation than DCPA-free calcium hydroxide preparation. We concluded therefore that a calcium hydroxide preparation containing DCPA is a promising alternative to the calcium hydroxide preparation currently used in dental clinics.

本文言語英語
ページ(範囲)434-439
ページ数6
ジャーナルJournal of the Ceramic Society of Japan
112
1308
DOI
出版ステータス出版済み - 8 2004

All Science Journal Classification (ASJC) codes

  • セラミックおよび複合材料
  • 化学 (全般)
  • 凝縮系物理学
  • 材料化学

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