Diagnostic significance of a dilated orifice of the duodenal papilla in intraductal papillary mucinous neoplasm of the pancreas

Teppei Aso, Ohtsuka Takao, Noboru Ideno, Hiroshi Kono, Yosuke Nagayoshi, Yasuhisa Mori, Kenoki Ouchida, Junji Ueda, Shunnichi Takahata, Katsuya Morimatsu, Shinichi Aishima, Hisato Igarashi, Tetsuhide Ito, Kosei Ishigami, Kazuhiro Mizumoto, Masao Tanaka

研究成果: ジャーナルへの寄稿記事

14 引用 (Scopus)

抄録

Background: A dilated orifice of the duodenal papilla found during screening endoscopy or ERCP is well-known as one of the specific findings of intraductal papillary mucinous neoplasm (IPMN). However, its clinical significance is still unclear. Objective: To assess the diagnostic significance of a dilated orifice of the duodenal papilla and evaluate whether this could be a factor predictive of malignancy or a subtype of IPMN. Design: Retrospective study. Setting: University hospital. Patients: This study involved 149 patients who underwent pancreatectomy for IPMN between January 1987 and June 2011. Intervention: ERCP. Main Outcome Measurements: The rate of malignant and intestinal type IPMNs in patients with and without papillary dilation. Results: A dilated orifice of the duodenal papilla was significantly associated with intestinal type IPMN (P <.001), but this finding could not predict the malignant grade of IPMN (P =.13). Multivariate analysis revealed that a dilated orifice was a significant factor for predicting intestinal type in both main duct (P =.01) and branch duct IPMNs (P <.001). Limitations: The validity of the definition of papillary dilation, selection bias, and a retrospective study. Conclusion: A dilated orifice of the duodenal papilla could be a significant factor for predicting intestinal type IPMN. This may lead to better clinical management of patients with IPMN.

元の言語英語
ページ(範囲)313-320
ページ数8
ジャーナルGastrointestinal endoscopy
76
発行部数2
DOI
出版物ステータス出版済み - 8 1 2012

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Pancreatic Neoplasms
Neoplasms
Endoscopic Retrograde Cholangiopancreatography
Dilatation
Retrospective Studies
Pancreatectomy
Selection Bias
Endoscopy
Multivariate Analysis

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology

これを引用

Diagnostic significance of a dilated orifice of the duodenal papilla in intraductal papillary mucinous neoplasm of the pancreas. / Aso, Teppei; Takao, Ohtsuka; Ideno, Noboru; Kono, Hiroshi; Nagayoshi, Yosuke; Mori, Yasuhisa; Ouchida, Kenoki; Ueda, Junji; Takahata, Shunnichi; Morimatsu, Katsuya; Aishima, Shinichi; Igarashi, Hisato; Ito, Tetsuhide; Ishigami, Kosei; Mizumoto, Kazuhiro; Tanaka, Masao.

:: Gastrointestinal endoscopy, 巻 76, 番号 2, 01.08.2012, p. 313-320.

研究成果: ジャーナルへの寄稿記事

Aso, T, Takao, O, Ideno, N, Kono, H, Nagayoshi, Y, Mori, Y, Ouchida, K, Ueda, J, Takahata, S, Morimatsu, K, Aishima, S, Igarashi, H, Ito, T, Ishigami, K, Mizumoto, K & Tanaka, M 2012, 'Diagnostic significance of a dilated orifice of the duodenal papilla in intraductal papillary mucinous neoplasm of the pancreas', Gastrointestinal endoscopy, 巻. 76, 番号 2, pp. 313-320. https://doi.org/10.1016/j.gie.2012.03.682
Aso, Teppei ; Takao, Ohtsuka ; Ideno, Noboru ; Kono, Hiroshi ; Nagayoshi, Yosuke ; Mori, Yasuhisa ; Ouchida, Kenoki ; Ueda, Junji ; Takahata, Shunnichi ; Morimatsu, Katsuya ; Aishima, Shinichi ; Igarashi, Hisato ; Ito, Tetsuhide ; Ishigami, Kosei ; Mizumoto, Kazuhiro ; Tanaka, Masao. / Diagnostic significance of a dilated orifice of the duodenal papilla in intraductal papillary mucinous neoplasm of the pancreas. :: Gastrointestinal endoscopy. 2012 ; 巻 76, 番号 2. pp. 313-320.
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T1 - Diagnostic significance of a dilated orifice of the duodenal papilla in intraductal papillary mucinous neoplasm of the pancreas

AU - Aso, Teppei

AU - Takao, Ohtsuka

AU - Ideno, Noboru

AU - Kono, Hiroshi

AU - Nagayoshi, Yosuke

AU - Mori, Yasuhisa

AU - Ouchida, Kenoki

AU - Ueda, Junji

AU - Takahata, Shunnichi

AU - Morimatsu, Katsuya

AU - Aishima, Shinichi

AU - Igarashi, Hisato

AU - Ito, Tetsuhide

AU - Ishigami, Kosei

AU - Mizumoto, Kazuhiro

AU - Tanaka, Masao

PY - 2012/8/1

Y1 - 2012/8/1

N2 - Background: A dilated orifice of the duodenal papilla found during screening endoscopy or ERCP is well-known as one of the specific findings of intraductal papillary mucinous neoplasm (IPMN). However, its clinical significance is still unclear. Objective: To assess the diagnostic significance of a dilated orifice of the duodenal papilla and evaluate whether this could be a factor predictive of malignancy or a subtype of IPMN. Design: Retrospective study. Setting: University hospital. Patients: This study involved 149 patients who underwent pancreatectomy for IPMN between January 1987 and June 2011. Intervention: ERCP. Main Outcome Measurements: The rate of malignant and intestinal type IPMNs in patients with and without papillary dilation. Results: A dilated orifice of the duodenal papilla was significantly associated with intestinal type IPMN (P <.001), but this finding could not predict the malignant grade of IPMN (P =.13). Multivariate analysis revealed that a dilated orifice was a significant factor for predicting intestinal type in both main duct (P =.01) and branch duct IPMNs (P <.001). Limitations: The validity of the definition of papillary dilation, selection bias, and a retrospective study. Conclusion: A dilated orifice of the duodenal papilla could be a significant factor for predicting intestinal type IPMN. This may lead to better clinical management of patients with IPMN.

AB - Background: A dilated orifice of the duodenal papilla found during screening endoscopy or ERCP is well-known as one of the specific findings of intraductal papillary mucinous neoplasm (IPMN). However, its clinical significance is still unclear. Objective: To assess the diagnostic significance of a dilated orifice of the duodenal papilla and evaluate whether this could be a factor predictive of malignancy or a subtype of IPMN. Design: Retrospective study. Setting: University hospital. Patients: This study involved 149 patients who underwent pancreatectomy for IPMN between January 1987 and June 2011. Intervention: ERCP. Main Outcome Measurements: The rate of malignant and intestinal type IPMNs in patients with and without papillary dilation. Results: A dilated orifice of the duodenal papilla was significantly associated with intestinal type IPMN (P <.001), but this finding could not predict the malignant grade of IPMN (P =.13). Multivariate analysis revealed that a dilated orifice was a significant factor for predicting intestinal type in both main duct (P =.01) and branch duct IPMNs (P <.001). Limitations: The validity of the definition of papillary dilation, selection bias, and a retrospective study. Conclusion: A dilated orifice of the duodenal papilla could be a significant factor for predicting intestinal type IPMN. This may lead to better clinical management of patients with IPMN.

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