Dietary conjugated linoleic acid increases endurance capacity and fat oxidation in mice during exercise

Wataru Mizunoya, Satoshi Haramizu, Tetsuro Shibakusa, Yuki Okabe, Tohru Fushiki

研究成果: ジャーナルへの寄稿記事

34 引用 (Scopus)

抄録

Ingestion of CLA activates β-oxidation and causes loss of body fat in rodents. We investigated the effects of dietary CLA on endurance capacity and energy metabolism during exercise in mice. Five-week-old male BALB/c mice were fed a control diet containing 1.0% linoleic acid or a diet containing 0.5% CLA that replaced an equivalent amount of linoleic acid for 1 wk. The maximum swimming time until fatigue was significantly higher in the CLA-fed group than in the control group. During treadmill running, the respiratory exchange ratio was significantly lower in the CLA-fed group, but oxygen consumption did not differ significantly between groups, suggesting that FA contributed more as an energy substrate in the CLA-fed mice. The muscle lipoprotein lipase activity was significantly higher in the CLA-fed group than in the control group. These results suggest that CLA ingestion increases endurance exercise capacity by promoting fat oxidation during exercise.

元の言語英語
ページ(範囲)265-271
ページ数7
ジャーナルLipids
40
発行部数3
DOI
出版物ステータス出版済み - 3 1 2005

Fingerprint

Conjugated Linoleic Acids
Durability
Fats
Linoleic Acid
Nutrition
Oxidation
Eating
Diet
Exercise equipment
Control Groups
Lipoprotein Lipase
Oxygen Consumption
Running
Energy Metabolism
Fatigue
Muscle
Adipose Tissue
Rodentia
Fatigue of materials
Oxygen

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Organic Chemistry
  • Cell Biology

これを引用

Dietary conjugated linoleic acid increases endurance capacity and fat oxidation in mice during exercise. / Mizunoya, Wataru; Haramizu, Satoshi; Shibakusa, Tetsuro; Okabe, Yuki; Fushiki, Tohru.

:: Lipids, 巻 40, 番号 3, 01.03.2005, p. 265-271.

研究成果: ジャーナルへの寄稿記事

Mizunoya, W, Haramizu, S, Shibakusa, T, Okabe, Y & Fushiki, T 2005, 'Dietary conjugated linoleic acid increases endurance capacity and fat oxidation in mice during exercise', Lipids, 巻. 40, 番号 3, pp. 265-271. https://doi.org/10.1007/s11745-005-1381-5
Mizunoya, Wataru ; Haramizu, Satoshi ; Shibakusa, Tetsuro ; Okabe, Yuki ; Fushiki, Tohru. / Dietary conjugated linoleic acid increases endurance capacity and fat oxidation in mice during exercise. :: Lipids. 2005 ; 巻 40, 番号 3. pp. 265-271.
@article{39f99a080d7a4d19a77d81953862325a,
title = "Dietary conjugated linoleic acid increases endurance capacity and fat oxidation in mice during exercise",
abstract = "Ingestion of CLA activates β-oxidation and causes loss of body fat in rodents. We investigated the effects of dietary CLA on endurance capacity and energy metabolism during exercise in mice. Five-week-old male BALB/c mice were fed a control diet containing 1.0{\%} linoleic acid or a diet containing 0.5{\%} CLA that replaced an equivalent amount of linoleic acid for 1 wk. The maximum swimming time until fatigue was significantly higher in the CLA-fed group than in the control group. During treadmill running, the respiratory exchange ratio was significantly lower in the CLA-fed group, but oxygen consumption did not differ significantly between groups, suggesting that FA contributed more as an energy substrate in the CLA-fed mice. The muscle lipoprotein lipase activity was significantly higher in the CLA-fed group than in the control group. These results suggest that CLA ingestion increases endurance exercise capacity by promoting fat oxidation during exercise.",
author = "Wataru Mizunoya and Satoshi Haramizu and Tetsuro Shibakusa and Yuki Okabe and Tohru Fushiki",
year = "2005",
month = "3",
day = "1",
doi = "10.1007/s11745-005-1381-5",
language = "English",
volume = "40",
pages = "265--271",
journal = "Lipids",
issn = "0024-4201",
publisher = "Springer Verlag",
number = "3",

}

TY - JOUR

T1 - Dietary conjugated linoleic acid increases endurance capacity and fat oxidation in mice during exercise

AU - Mizunoya, Wataru

AU - Haramizu, Satoshi

AU - Shibakusa, Tetsuro

AU - Okabe, Yuki

AU - Fushiki, Tohru

PY - 2005/3/1

Y1 - 2005/3/1

N2 - Ingestion of CLA activates β-oxidation and causes loss of body fat in rodents. We investigated the effects of dietary CLA on endurance capacity and energy metabolism during exercise in mice. Five-week-old male BALB/c mice were fed a control diet containing 1.0% linoleic acid or a diet containing 0.5% CLA that replaced an equivalent amount of linoleic acid for 1 wk. The maximum swimming time until fatigue was significantly higher in the CLA-fed group than in the control group. During treadmill running, the respiratory exchange ratio was significantly lower in the CLA-fed group, but oxygen consumption did not differ significantly between groups, suggesting that FA contributed more as an energy substrate in the CLA-fed mice. The muscle lipoprotein lipase activity was significantly higher in the CLA-fed group than in the control group. These results suggest that CLA ingestion increases endurance exercise capacity by promoting fat oxidation during exercise.

AB - Ingestion of CLA activates β-oxidation and causes loss of body fat in rodents. We investigated the effects of dietary CLA on endurance capacity and energy metabolism during exercise in mice. Five-week-old male BALB/c mice were fed a control diet containing 1.0% linoleic acid or a diet containing 0.5% CLA that replaced an equivalent amount of linoleic acid for 1 wk. The maximum swimming time until fatigue was significantly higher in the CLA-fed group than in the control group. During treadmill running, the respiratory exchange ratio was significantly lower in the CLA-fed group, but oxygen consumption did not differ significantly between groups, suggesting that FA contributed more as an energy substrate in the CLA-fed mice. The muscle lipoprotein lipase activity was significantly higher in the CLA-fed group than in the control group. These results suggest that CLA ingestion increases endurance exercise capacity by promoting fat oxidation during exercise.

UR - http://www.scopus.com/inward/record.url?scp=18244380840&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=18244380840&partnerID=8YFLogxK

U2 - 10.1007/s11745-005-1381-5

DO - 10.1007/s11745-005-1381-5

M3 - Article

C2 - 15957252

AN - SCOPUS:18244380840

VL - 40

SP - 265

EP - 271

JO - Lipids

JF - Lipids

SN - 0024-4201

IS - 3

ER -