Dietary effect of EPA-rich and DHA-rich fish oils on the immune function of sprague-dawley rats

Pham Hung, Shihoko Kaku, Shin Ichi Yunoki, Ken Ichi Ohkura, Jiongyan Gu, Ikuo Ikeda, Michihiro Sugano, Kazunaga Yazawa, Koji Yamada

研究成果: ジャーナルへの寄稿記事

35 引用 (Scopus)

抄録

The dietary effect of fish oils (FOs) rich in eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA) on the immune function of Sprague-Dawley rats was compared with that of safflower oil. After 3 weeks of feeding at the 10% level of a dietary fat, the IgG and IgM production by splenocytes and IgG production by mesenteric lymph node (MLN) lymphocytes were significantly higher in the FO-fed rats, while no significant difference was found in IgA or IgE productivity by both the spleen and MLN lymphocytes. In the FO-fed rats, peritoneal exudate cells released a lower amount of LTB4, reflecting their lower arachidonic acid level, and a higher amount of LTB5, reflecting their higher EPA level in phospholipids. On these EPA-rich FO exerted a stronger effect than DHA-rich FO immune functions.

元の言語英語
ページ(範囲)135-140
ページ数6
ジャーナルBioscience, Biotechnology and Biochemistry
63
発行部数1
DOI
出版物ステータス出版済み - 1 1 1999

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Eicosapentaenoic Acid
Docosahexaenoic Acids
Fish Oils
Sprague Dawley Rats
Rats
Lymphocytes
Immunoglobulin G
Lymph Nodes
Safflower Oil
Leukotriene B4
Dietary Fats
Exudates and Transudates
Arachidonic Acid
Immunoglobulin A
Immunoglobulin E
Immunoglobulin M
Phospholipids
Spleen
Productivity

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

これを引用

Dietary effect of EPA-rich and DHA-rich fish oils on the immune function of sprague-dawley rats. / Hung, Pham; Kaku, Shihoko; Yunoki, Shin Ichi; Ohkura, Ken Ichi; Gu, Jiongyan; Ikeda, Ikuo; Sugano, Michihiro; Yazawa, Kazunaga; Yamada, Koji.

:: Bioscience, Biotechnology and Biochemistry, 巻 63, 番号 1, 01.01.1999, p. 135-140.

研究成果: ジャーナルへの寄稿記事

Hung, P, Kaku, S, Yunoki, SI, Ohkura, KI, Gu, J, Ikeda, I, Sugano, M, Yazawa, K & Yamada, K 1999, 'Dietary effect of EPA-rich and DHA-rich fish oils on the immune function of sprague-dawley rats', Bioscience, Biotechnology and Biochemistry, 巻. 63, 番号 1, pp. 135-140. https://doi.org/10.1271/bbb.63.135
Hung, Pham ; Kaku, Shihoko ; Yunoki, Shin Ichi ; Ohkura, Ken Ichi ; Gu, Jiongyan ; Ikeda, Ikuo ; Sugano, Michihiro ; Yazawa, Kazunaga ; Yamada, Koji. / Dietary effect of EPA-rich and DHA-rich fish oils on the immune function of sprague-dawley rats. :: Bioscience, Biotechnology and Biochemistry. 1999 ; 巻 63, 番号 1. pp. 135-140.
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AU - Gu, Jiongyan

AU - Ikeda, Ikuo

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