The combination of transcranial magnetic stimulation (TMS) and electroencephalogram (EEG) is an effective tool for investigating the cortical reactivity and the functional connectivity in the brain. In our previous study, we reported a method of removing stimulus artifact during TMS with Sample-and-Hold circuit and EEG activity evoked by TMS could be measured successfully. In addition to this method, independent component analysis (ICA) was also applied to recorded EEG data in order to remove the stimulus artifact from for off-line analysis. By using these methods, short latency ( 15 ms) EEG responses to TMS could be obtained. In this paper, we focused on the propagation of EEG activity elicited by TMS. We observed both the EEG topography and the distribution of the current density over the whole head by changing the stimulus site. When motor cortex was stimulated, the propagation of EEG activity to contralateral hemisphere could be clearly observed. However, when posterior parietal cortex was stimulated, no or less propagation of EEG responses could be recognized. These results suggest that the responses evoked by TMS over motor cortex propagate to contralateral hemisphere along the axon through the corpus callosum.
|ジャーナル||Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings|
|出版ステータス||出版済み - 2008|
All Science Journal Classification (ASJC) codes
- Computer Vision and Pattern Recognition
- Signal Processing
- Biomedical Engineering
- Health Informatics