抄録
Effects of thymectomy at various times after birth on cytotoxicity, delayed footpad reaction and antibody production were examined in 6 week old mice immunized intraperitoneally with chicken erythrocytes. Cytotoxicity and antibody production were abolished by thymectomy within 3 days after birth. Mice thymectomized at 5 days of age or later showed appreciable degrees of cytotoxicity and antibody production. On the other hand, a delayed footpad reaction could be elicited even in mice thymectomized within 24 h after birth, although the degree of the reaction was reduced by such a treatment. Therefore, T cells responsible for delayed hypersensitivity were less thymus-dependent and required the presence of the thymus for a shorter period in their development that those responsible for cytotoxicity or antibody production.
本文言語 | 英語 |
---|---|
ページ(範囲) | 167-178 |
ページ数 | 12 |
ジャーナル | Immunology |
巻 | 41 |
号 | 1 |
出版ステータス | 出版済み - 1980 |
外部発表 | はい |
!!!All Science Journal Classification (ASJC) codes
- 免疫アレルギー学
- 免疫学