TY - JOUR
T1 - Differential effects of five types of antipathogenic plant peptides on model membranes
AU - Caaveiro, José Manuel M.
AU - Molina, Antonio
AU - González-Mañas, Juan M.
AU - Rodríguez-Palenzuela, Pablo
AU - García-Olmedo, Francisco
AU - Goñi, Félix M.
N1 - Funding Information:
This work was supported in part by grants from DGICYT (PB91-0441) (F.M.G.), University of the Basque Country (UPV 042.310-EB218/95) (J.M.G.M.), and DGICYT (PB92-0325) (F.G.O.). J.M.M.C. was a recipient of a scholarship from the Basque Government.
PY - 1997/6/30
Y1 - 1997/6/30
N2 - The effects of five antipathogenic plant peptides, wheat α-thionin, potato PTH1 defensin, barley LTP2 lipid transfer protein, and potato tuber DL1 and DL2 defensins, have been tested against phospholipid vesicles (liposomes). Wheat thionin very actively induces aggregation and leakage of negatively charged vesicles. LTP2 displays the same activities, although to a limited extent. Under certain conditions PTH1 and DL2 induce vesicle aggregation, but not leakage. Potato defensin DL1 failed to show any effect on liposomes. The same peptides have been assayed against a plant pathogenic bacterium, both the membrane-active and -inactive compounds having efficient antibacterial action.
AB - The effects of five antipathogenic plant peptides, wheat α-thionin, potato PTH1 defensin, barley LTP2 lipid transfer protein, and potato tuber DL1 and DL2 defensins, have been tested against phospholipid vesicles (liposomes). Wheat thionin very actively induces aggregation and leakage of negatively charged vesicles. LTP2 displays the same activities, although to a limited extent. Under certain conditions PTH1 and DL2 induce vesicle aggregation, but not leakage. Potato defensin DL1 failed to show any effect on liposomes. The same peptides have been assayed against a plant pathogenic bacterium, both the membrane-active and -inactive compounds having efficient antibacterial action.
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U2 - 10.1016/S0014-5793(97)00613-3
DO - 10.1016/S0014-5793(97)00613-3
M3 - Article
C2 - 9237658
AN - SCOPUS:0030871334
SN - 0014-5793
VL - 410
SP - 338
EP - 342
JO - FEBS Letters
JF - FEBS Letters
IS - 2-3
ER -