Differentiation of periodontal ligament stem/progenitor cells: Roles of TGF-β1

Hidefumi Maeda, Shinsuke Fujii, Satoshi Monnouchi, Naohisa Wada, Akifumi Akamine

研究成果: 著書/レポートタイプへの貢献

1 引用 (Scopus)

抄録

Tooth loss provokes loss of occlusal function, resulting in a decreased quality of life. Tooth loss is related primarily to irretrievable damage of the periodontium caused by deep caries, severe periodontal diseases, or irreversible trauma. Periodontal ligament (PDL) is a central tissue in periodontium and contains stem/progenitor cells that are believed to have the potential to regenerate periodontium, including PDL tissue. For this reason, we and other groups have focused on such undifferentiated cells to elucidate their applicable potentials for PDL regenerative medicine based on cell-based tissue engineering. However, how their differentiation is controlled remains unclear. We recently suggested that transforming growth factor-beta 1 is a candidate factor for regulation of fibroblastic differentiation of stem/progenitor cells in PDL tissue.

元の言語英語
ホスト出版物のタイトルStem Cells and Cancer Stem Cells, Volume 4
ホスト出版物のサブタイトルTherapeutic Applications in Disease and Injury
出版者Springer Netherlands
ページ51-58
ページ数8
ISBN(電子版)9789400728288
ISBN(印刷物)9789400728271
DOI
出版物ステータス出版済み - 1 1 2012

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Periodontal Ligament
Periodontium
Stem Cells
Tooth Loss
Regenerative Medicine
Periodontal Diseases
Tissue Engineering
Transforming Growth Factor beta
Quality of Life
Wounds and Injuries

All Science Journal Classification (ASJC) codes

  • Medicine(all)

これを引用

Maeda, H., Fujii, S., Monnouchi, S., Wada, N., & Akamine, A. (2012). Differentiation of periodontal ligament stem/progenitor cells: Roles of TGF-β1. : Stem Cells and Cancer Stem Cells, Volume 4: Therapeutic Applications in Disease and Injury (pp. 51-58). Springer Netherlands. https://doi.org/10.1007/978-94-007-2828-8_5

Differentiation of periodontal ligament stem/progenitor cells : Roles of TGF-β1. / Maeda, Hidefumi; Fujii, Shinsuke; Monnouchi, Satoshi; Wada, Naohisa; Akamine, Akifumi.

Stem Cells and Cancer Stem Cells, Volume 4: Therapeutic Applications in Disease and Injury. Springer Netherlands, 2012. p. 51-58.

研究成果: 著書/レポートタイプへの貢献

Maeda, H, Fujii, S, Monnouchi, S, Wada, N & Akamine, A 2012, Differentiation of periodontal ligament stem/progenitor cells: Roles of TGF-β1. : Stem Cells and Cancer Stem Cells, Volume 4: Therapeutic Applications in Disease and Injury. Springer Netherlands, pp. 51-58. https://doi.org/10.1007/978-94-007-2828-8_5
Maeda H, Fujii S, Monnouchi S, Wada N, Akamine A. Differentiation of periodontal ligament stem/progenitor cells: Roles of TGF-β1. : Stem Cells and Cancer Stem Cells, Volume 4: Therapeutic Applications in Disease and Injury. Springer Netherlands. 2012. p. 51-58 https://doi.org/10.1007/978-94-007-2828-8_5
Maeda, Hidefumi ; Fujii, Shinsuke ; Monnouchi, Satoshi ; Wada, Naohisa ; Akamine, Akifumi. / Differentiation of periodontal ligament stem/progenitor cells : Roles of TGF-β1. Stem Cells and Cancer Stem Cells, Volume 4: Therapeutic Applications in Disease and Injury. Springer Netherlands, 2012. pp. 51-58
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