Diffusivity of intraorbital lymphoma vs. inflammation: comparison of single shot turbo spin echo and multishot echo planar imaging techniques

Akio Hiwatashi, Osamu Togao, Koji Yamashita, Kazufumi Kikuchi, Ryotaro Kamei, Hiroshi Yoshikawa, Atsushi Takemura, Hiroshi Honda

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)

抄録

Purpose: To compare the abilities of turbo spin-echo diffusion-weighted imaging (TSE DWI) and multi-shot echo planar DWI (MSh DWI) to discriminate orbital lymphoma from inflammatory lesions. Materials and methods: Twenty-nine patients with pathologically confirmed lymphomas and 39 patients with inflammation were imaged with a 3.0-T system. The apparent diffusion coefficient (ADC) of each lesion was measured. Signal intensities compared to normal grey matter on conventional imaging were also measured. Results: The ADCs derived from the TSE DWI of the lymphomas (0.68 ± 0.14 × 10−3 mm2/s) were significantly lower than those of the inflammation cases (1.04 ± 0.39 × 10−3 mm2/s; p < 0.001). The ADCs derived from MSh DWI could not be used to separate the lymphomas from the inflammation (1.16 ± 0.43 × 10−3 mm2/s vs. 1.36 ± 0.48 × 10−3 mm2/s; p = 0.06). Conventional sequences also could not separate the lymphomas from the inflammation (p > 0.05). The ROC analysis showed the best diagnostic performance with ADCs derived from TSE DWI (the area under the curve: AUC = 0.831) followed by ADC derived from MSh DWI (AUC = 0.633). Conclusion: The ADCs derived from TSE DWI might help to differentiate orbital lymphomas from inflammation. Key Points: • ADC of lymphoma was significantly lower than that of inflammation. • ADC derived from TSE DWI showed the best diagnostic performance. • This study was conducted by a 3-T MR scanner.

元の言語英語
ページ(範囲)325-330
ページ数6
ジャーナルEuropean Radiology
28
発行部数1
DOI
出版物ステータス出版済み - 1 1 2018

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Echo-Planar Imaging
Lymphoma
Inflammation
Area Under Curve
ROC Curve

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

これを引用

Diffusivity of intraorbital lymphoma vs. inflammation : comparison of single shot turbo spin echo and multishot echo planar imaging techniques. / Hiwatashi, Akio; Togao, Osamu; Yamashita, Koji; Kikuchi, Kazufumi; Kamei, Ryotaro; Yoshikawa, Hiroshi; Takemura, Atsushi; Honda, Hiroshi.

:: European Radiology, 巻 28, 番号 1, 01.01.2018, p. 325-330.

研究成果: ジャーナルへの寄稿記事

Hiwatashi, Akio ; Togao, Osamu ; Yamashita, Koji ; Kikuchi, Kazufumi ; Kamei, Ryotaro ; Yoshikawa, Hiroshi ; Takemura, Atsushi ; Honda, Hiroshi. / Diffusivity of intraorbital lymphoma vs. inflammation : comparison of single shot turbo spin echo and multishot echo planar imaging techniques. :: European Radiology. 2018 ; 巻 28, 番号 1. pp. 325-330.
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abstract = "Purpose: To compare the abilities of turbo spin-echo diffusion-weighted imaging (TSE DWI) and multi-shot echo planar DWI (MSh DWI) to discriminate orbital lymphoma from inflammatory lesions. Materials and methods: Twenty-nine patients with pathologically confirmed lymphomas and 39 patients with inflammation were imaged with a 3.0-T system. The apparent diffusion coefficient (ADC) of each lesion was measured. Signal intensities compared to normal grey matter on conventional imaging were also measured. Results: The ADCs derived from the TSE DWI of the lymphomas (0.68 ± 0.14 × 10−3 mm2/s) were significantly lower than those of the inflammation cases (1.04 ± 0.39 × 10−3 mm2/s; p < 0.001). The ADCs derived from MSh DWI could not be used to separate the lymphomas from the inflammation (1.16 ± 0.43 × 10−3 mm2/s vs. 1.36 ± 0.48 × 10−3 mm2/s; p = 0.06). Conventional sequences also could not separate the lymphomas from the inflammation (p > 0.05). The ROC analysis showed the best diagnostic performance with ADCs derived from TSE DWI (the area under the curve: AUC = 0.831) followed by ADC derived from MSh DWI (AUC = 0.633). Conclusion: The ADCs derived from TSE DWI might help to differentiate orbital lymphomas from inflammation. Key Points: • ADC of lymphoma was significantly lower than that of inflammation. • ADC derived from TSE DWI showed the best diagnostic performance. • This study was conducted by a 3-T MR scanner.",
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AU - Yamashita, Koji

AU - Kikuchi, Kazufumi

AU - Kamei, Ryotaro

AU - Yoshikawa, Hiroshi

AU - Takemura, Atsushi

AU - Honda, Hiroshi

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N2 - Purpose: To compare the abilities of turbo spin-echo diffusion-weighted imaging (TSE DWI) and multi-shot echo planar DWI (MSh DWI) to discriminate orbital lymphoma from inflammatory lesions. Materials and methods: Twenty-nine patients with pathologically confirmed lymphomas and 39 patients with inflammation were imaged with a 3.0-T system. The apparent diffusion coefficient (ADC) of each lesion was measured. Signal intensities compared to normal grey matter on conventional imaging were also measured. Results: The ADCs derived from the TSE DWI of the lymphomas (0.68 ± 0.14 × 10−3 mm2/s) were significantly lower than those of the inflammation cases (1.04 ± 0.39 × 10−3 mm2/s; p < 0.001). The ADCs derived from MSh DWI could not be used to separate the lymphomas from the inflammation (1.16 ± 0.43 × 10−3 mm2/s vs. 1.36 ± 0.48 × 10−3 mm2/s; p = 0.06). Conventional sequences also could not separate the lymphomas from the inflammation (p > 0.05). The ROC analysis showed the best diagnostic performance with ADCs derived from TSE DWI (the area under the curve: AUC = 0.831) followed by ADC derived from MSh DWI (AUC = 0.633). Conclusion: The ADCs derived from TSE DWI might help to differentiate orbital lymphomas from inflammation. Key Points: • ADC of lymphoma was significantly lower than that of inflammation. • ADC derived from TSE DWI showed the best diagnostic performance. • This study was conducted by a 3-T MR scanner.

AB - Purpose: To compare the abilities of turbo spin-echo diffusion-weighted imaging (TSE DWI) and multi-shot echo planar DWI (MSh DWI) to discriminate orbital lymphoma from inflammatory lesions. Materials and methods: Twenty-nine patients with pathologically confirmed lymphomas and 39 patients with inflammation were imaged with a 3.0-T system. The apparent diffusion coefficient (ADC) of each lesion was measured. Signal intensities compared to normal grey matter on conventional imaging were also measured. Results: The ADCs derived from the TSE DWI of the lymphomas (0.68 ± 0.14 × 10−3 mm2/s) were significantly lower than those of the inflammation cases (1.04 ± 0.39 × 10−3 mm2/s; p < 0.001). The ADCs derived from MSh DWI could not be used to separate the lymphomas from the inflammation (1.16 ± 0.43 × 10−3 mm2/s vs. 1.36 ± 0.48 × 10−3 mm2/s; p = 0.06). Conventional sequences also could not separate the lymphomas from the inflammation (p > 0.05). The ROC analysis showed the best diagnostic performance with ADCs derived from TSE DWI (the area under the curve: AUC = 0.831) followed by ADC derived from MSh DWI (AUC = 0.633). Conclusion: The ADCs derived from TSE DWI might help to differentiate orbital lymphomas from inflammation. Key Points: • ADC of lymphoma was significantly lower than that of inflammation. • ADC derived from TSE DWI showed the best diagnostic performance. • This study was conducted by a 3-T MR scanner.

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