Disseminated lichen sclerosus of the trunk and upper extremities

Akiko Masuda, Takamichi Ito, Kazuko Doi, Masutaka Furue

研究成果: Contribution to journalArticle査読

抄録

A 41-year-old Japanese woman presented with a 4-year history of multiple white atrophic plaques. The lesions had occurred on the right upper arm as white papules of 2-3 mm in diameter, which had gradually become enlarged and spread to the right upper back and the neck. Physical examination revealed that the lesion on the right upper back was accompanied by erythema and erosions. Similar lesions were observed on the neck, chest, right forearm, and genital area. Dermoscopically, each lesion mainly consisted of a "whitish patch" and follicular pigmentation. No obvious "comedo-like opening" was noted. Histopathologic examination revealed atrophic epidermis, hyperkeratosis in the horny layer, edematous stroma, and homogenous collagenous tissue in the upper dermis. On the basis of these findings, a diagnosis of multiple lichen sclerosus was made. We started treatment with topical betamethasone butyrate propionate ointment (Antebate® ointment, 0.05%) for 2 weeks, followed by treatment with topical tacrolimus ointment (Protopic® ointment, 0.1%). The erosions and pain in the plaques disappeared after 6 weeks. In the current case, it is of interest that topical tacrolimus ointment was effective for extragenital lichen sclerosus. Dermoscopy may be useful to assist with diagnosis, but we should bear in mind that the dermoscopic findings of lichen sclerosus vary by the stage and location of the lesions.

本文言語英語
ページ(範囲)479-482
ページ数4
ジャーナルNishinihon Journal of Dermatology
77
5
DOI
出版ステータス出版済み - 2015

All Science Journal Classification (ASJC) codes

  • 皮膚病学

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