Dissociable contributions of MRI volume reductions of superior temporal and fusiform gyri to symptoms and neuropsychology in schizophrenia

Paul G. Nestor, Toshiaki Onitsuka, Ronald J. Gurrera, Margaret Niznikiewicz, Melissa Frumin, Martha E. Shenton, Robert W. McCarley

研究成果: Contribution to journalArticle査読

40 被引用数 (Scopus)

抄録

We sought to identify the functional correlates of reduced magnetic resonance imaging (MRI) volumes of the superior temporal gyrus (STG) and the fusiform gyrus (FG) in patients with chronic schizophrenia. MRI volumes, positive/negative symptoms, and neuropsychological tests of facial memory and executive functioning were examined within the same subjects. The results indicated two distinct, dissociable brain structure-function relationships: (1) reduced left STG volume-positive symptoms-executive deficits; (2) reduced left FG-negative symptoms-facial memory deficits. STG and FG volume reductions may each make distinct contributions to symptoms and cognitive deficits of schizophrenia.

本文言語英語
ページ(範囲)103-106
ページ数4
ジャーナルSchizophrenia research
91
1-3
DOI
出版ステータス出版済み - 3 2007
外部発表はい

All Science Journal Classification (ASJC) codes

  • 精神医学および精神衛生
  • 生物学的精神医学

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