Disuse Atrophy of the Aortic Valve After Left Ventricular Assist Device Implantation

Tomoki Ushijima, Yoshihisa Tanoue, Tomomi Ide, Shinji Okano, Yoshinao Oda, Ryuji Tominaga

研究成果: Contribution to journalArticle査読

2 被引用数 (Scopus)

抄録

A 31-year-old woman underwent implantation of a DuraHeart left ventricular assist device as bridge to transplantation. Aortic insufficiency was not observed before implantation but developed after implantation and became severe approximately 2 years later. Macroscopically, the aortic valve excised during heart transplantation showed no morphologic alteration. Microscopically, the collagen fibers in the fibrosa layer and the elastic fibers in the ventricularis layer of the valve leaflets were reduced in number, with irregular arrangement. These characteristics can be explained by a disuse atrophic change, and may lead to a better understanding of the mechanism underlying the development of aortic insufficiency.

本文言語英語
ページ(範囲)742-744
ページ数3
ジャーナルAnnals of Thoracic Surgery
101
2
DOI
出版ステータス出版済み - 2 1 2016

All Science Journal Classification (ASJC) codes

  • 外科
  • 呼吸器内科
  • 循環器および心血管医学

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