Divergent histology in the primary and metastatic lesions of thyroid carcinoma

T. Harada, T. Mimura, K. Ito, Yoichi Nakanishi, T. Senoo, Y. Hosoda, K. Yakumaru, C. Tsukayama

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

抄録

The metastatic lesions of malignant diseases tend to present similar histological findings as the primary tumor. However, thyroid carcinoma is one of the malignancies which may be an exception to this rule. We have reviewed 61 consecutive autopsies of thyroid cancer patients at the Ito Hospital and Kawasaki Medical School Hospital during a period between 1969-1982. Fifty-five of 61 cases of thyroid carcinoma were found to have metastatic spreads beyond the thyroid. The uniform pathological findings were present in 5 of 9 papillary adenocarcinomas, 14 of 15 anaplastic carcinomas, and 1 of two squamous cell carcinoma and one epidermoid carcinoma. The remaining 36 patients were found to have different histological findings in metastatic lesions from the primary tumor. The histological types in coexisting metastases varied from one lesion to the other; the primary tumor was adenocarcinoma, but one of the metastases was anaplastic and the others showed adenocarcinoma or its combination. Those histological divergence in the primary tumor and metastases can be considered as the results of anaplastic or squamous cell transformation from adenocarcinoma. Such alteration of the histological findings in thyroid carcinoma calls for the reassessment of the therapeutic strategy.

元の言語英語
ページ(範囲)758-761
ページ数4
ジャーナルNippon Geka Gakkai zasshi
84
発行部数9
出版物ステータス出版済み - 9 1 1983

Fingerprint

Thyroid Neoplasms
Histology
Adenocarcinoma
Neoplasms
Neoplasm Metastasis
Squamous Cell Carcinoma
Papillary Adenocarcinoma
Medical Schools
Autopsy
Thyroid Gland
Epithelial Cells
Carcinoma
Therapeutics

All Science Journal Classification (ASJC) codes

  • Medicine(all)

これを引用

Harada, T., Mimura, T., Ito, K., Nakanishi, Y., Senoo, T., Hosoda, Y., ... Tsukayama, C. (1983). Divergent histology in the primary and metastatic lesions of thyroid carcinoma. Nippon Geka Gakkai zasshi, 84(9), 758-761.

Divergent histology in the primary and metastatic lesions of thyroid carcinoma. / Harada, T.; Mimura, T.; Ito, K.; Nakanishi, Yoichi; Senoo, T.; Hosoda, Y.; Yakumaru, K.; Tsukayama, C.

:: Nippon Geka Gakkai zasshi, 巻 84, 番号 9, 01.09.1983, p. 758-761.

研究成果: ジャーナルへの寄稿記事

Harada, T, Mimura, T, Ito, K, Nakanishi, Y, Senoo, T, Hosoda, Y, Yakumaru, K & Tsukayama, C 1983, 'Divergent histology in the primary and metastatic lesions of thyroid carcinoma', Nippon Geka Gakkai zasshi, 巻. 84, 番号 9, pp. 758-761.
Harada T, Mimura T, Ito K, Nakanishi Y, Senoo T, Hosoda Y その他. Divergent histology in the primary and metastatic lesions of thyroid carcinoma. Nippon Geka Gakkai zasshi. 1983 9 1;84(9):758-761.
Harada, T. ; Mimura, T. ; Ito, K. ; Nakanishi, Yoichi ; Senoo, T. ; Hosoda, Y. ; Yakumaru, K. ; Tsukayama, C. / Divergent histology in the primary and metastatic lesions of thyroid carcinoma. :: Nippon Geka Gakkai zasshi. 1983 ; 巻 84, 番号 9. pp. 758-761.
@article{87cc24fb06394f558d530e2913c213b8,
title = "Divergent histology in the primary and metastatic lesions of thyroid carcinoma",
abstract = "The metastatic lesions of malignant diseases tend to present similar histological findings as the primary tumor. However, thyroid carcinoma is one of the malignancies which may be an exception to this rule. We have reviewed 61 consecutive autopsies of thyroid cancer patients at the Ito Hospital and Kawasaki Medical School Hospital during a period between 1969-1982. Fifty-five of 61 cases of thyroid carcinoma were found to have metastatic spreads beyond the thyroid. The uniform pathological findings were present in 5 of 9 papillary adenocarcinomas, 14 of 15 anaplastic carcinomas, and 1 of two squamous cell carcinoma and one epidermoid carcinoma. The remaining 36 patients were found to have different histological findings in metastatic lesions from the primary tumor. The histological types in coexisting metastases varied from one lesion to the other; the primary tumor was adenocarcinoma, but one of the metastases was anaplastic and the others showed adenocarcinoma or its combination. Those histological divergence in the primary tumor and metastases can be considered as the results of anaplastic or squamous cell transformation from adenocarcinoma. Such alteration of the histological findings in thyroid carcinoma calls for the reassessment of the therapeutic strategy.",
author = "T. Harada and T. Mimura and K. Ito and Yoichi Nakanishi and T. Senoo and Y. Hosoda and K. Yakumaru and C. Tsukayama",
year = "1983",
month = "9",
day = "1",
language = "English",
volume = "84",
pages = "758--761",
journal = "Nihon Geka Gakkai zasshi",
issn = "0301-4894",
publisher = "Nihon Geka Gakkai",
number = "9",

}

TY - JOUR

T1 - Divergent histology in the primary and metastatic lesions of thyroid carcinoma

AU - Harada, T.

AU - Mimura, T.

AU - Ito, K.

AU - Nakanishi, Yoichi

AU - Senoo, T.

AU - Hosoda, Y.

AU - Yakumaru, K.

AU - Tsukayama, C.

PY - 1983/9/1

Y1 - 1983/9/1

N2 - The metastatic lesions of malignant diseases tend to present similar histological findings as the primary tumor. However, thyroid carcinoma is one of the malignancies which may be an exception to this rule. We have reviewed 61 consecutive autopsies of thyroid cancer patients at the Ito Hospital and Kawasaki Medical School Hospital during a period between 1969-1982. Fifty-five of 61 cases of thyroid carcinoma were found to have metastatic spreads beyond the thyroid. The uniform pathological findings were present in 5 of 9 papillary adenocarcinomas, 14 of 15 anaplastic carcinomas, and 1 of two squamous cell carcinoma and one epidermoid carcinoma. The remaining 36 patients were found to have different histological findings in metastatic lesions from the primary tumor. The histological types in coexisting metastases varied from one lesion to the other; the primary tumor was adenocarcinoma, but one of the metastases was anaplastic and the others showed adenocarcinoma or its combination. Those histological divergence in the primary tumor and metastases can be considered as the results of anaplastic or squamous cell transformation from adenocarcinoma. Such alteration of the histological findings in thyroid carcinoma calls for the reassessment of the therapeutic strategy.

AB - The metastatic lesions of malignant diseases tend to present similar histological findings as the primary tumor. However, thyroid carcinoma is one of the malignancies which may be an exception to this rule. We have reviewed 61 consecutive autopsies of thyroid cancer patients at the Ito Hospital and Kawasaki Medical School Hospital during a period between 1969-1982. Fifty-five of 61 cases of thyroid carcinoma were found to have metastatic spreads beyond the thyroid. The uniform pathological findings were present in 5 of 9 papillary adenocarcinomas, 14 of 15 anaplastic carcinomas, and 1 of two squamous cell carcinoma and one epidermoid carcinoma. The remaining 36 patients were found to have different histological findings in metastatic lesions from the primary tumor. The histological types in coexisting metastases varied from one lesion to the other; the primary tumor was adenocarcinoma, but one of the metastases was anaplastic and the others showed adenocarcinoma or its combination. Those histological divergence in the primary tumor and metastases can be considered as the results of anaplastic or squamous cell transformation from adenocarcinoma. Such alteration of the histological findings in thyroid carcinoma calls for the reassessment of the therapeutic strategy.

UR - http://www.scopus.com/inward/record.url?scp=0020821566&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020821566&partnerID=8YFLogxK

M3 - Article

C2 - 6676642

AN - SCOPUS:0020821566

VL - 84

SP - 758

EP - 761

JO - Nihon Geka Gakkai zasshi

JF - Nihon Geka Gakkai zasshi

SN - 0301-4894

IS - 9

ER -