Diversity in copy number and structure of a silkworm morphogenetic gene as a result of domestication

Takashi Sakudoh, Takeharu Nakashima, Yoko Kuroki, Asao Fujiyama, Yuji Kohara, Naoko Honda, Hirofumi Fujimoto, Toru Shimada, Masao Nakagaki, Yutaka Banno, Kozo Tsuchida

研究成果: ジャーナルへの寄稿記事

13 引用 (Scopus)

抄録

The carotenoid-binding protein (CBP) of the domesticated silkworm, Bombyx mori, a major determinant of cocoon color, is likely to have been substantially influenced by domestication of this species. We analyzed the structure of the CBP gene in multiple strains of B. mori, in multiple individuals of the wild silkworm, B. mandarina (the putative wild ancestor of B. mori), and in a number of other lepidopterans. We found the CBP gene copy number in genomic DNA to vary widely among B. mori strains, ranging from 1 to 20. The copies of CBP are of several types, based on the presence of a retrotransposon or partial deletion of the coding sequence. In contrast to B. mori, B. mandarina was found to possess a single copy of CBP without the retrotransposon insertion, regardless of habitat. Several other lepidopterans were found to contain sequences homologous to CBP, revealing that this gene is evolutionarily conserved in the lepidopteran lineage. Thus, domestication can generate significant diversity of gene copy number and structure over a relatively short evolutionary time.

元の言語英語
ページ(範囲)965-976
ページ数12
ジャーナルGenetics
187
発行部数3
DOI
出版物ステータス出版済み - 3 1 2011

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Bombyx
Carotenoids
Carrier Proteins
Genes
Retroelements
Gene Dosage
Sequence Deletion
Sequence Homology
Domestication
Ecosystem
Color
DNA

All Science Journal Classification (ASJC) codes

  • Genetics

これを引用

Sakudoh, T., Nakashima, T., Kuroki, Y., Fujiyama, A., Kohara, Y., Honda, N., ... Tsuchida, K. (2011). Diversity in copy number and structure of a silkworm morphogenetic gene as a result of domestication. Genetics, 187(3), 965-976. https://doi.org/10.1534/genetics.110.124982

Diversity in copy number and structure of a silkworm morphogenetic gene as a result of domestication. / Sakudoh, Takashi; Nakashima, Takeharu; Kuroki, Yoko; Fujiyama, Asao; Kohara, Yuji; Honda, Naoko; Fujimoto, Hirofumi; Shimada, Toru; Nakagaki, Masao; Banno, Yutaka; Tsuchida, Kozo.

:: Genetics, 巻 187, 番号 3, 01.03.2011, p. 965-976.

研究成果: ジャーナルへの寄稿記事

Sakudoh, T, Nakashima, T, Kuroki, Y, Fujiyama, A, Kohara, Y, Honda, N, Fujimoto, H, Shimada, T, Nakagaki, M, Banno, Y & Tsuchida, K 2011, 'Diversity in copy number and structure of a silkworm morphogenetic gene as a result of domestication', Genetics, 巻. 187, 番号 3, pp. 965-976. https://doi.org/10.1534/genetics.110.124982
Sakudoh T, Nakashima T, Kuroki Y, Fujiyama A, Kohara Y, Honda N その他. Diversity in copy number and structure of a silkworm morphogenetic gene as a result of domestication. Genetics. 2011 3 1;187(3):965-976. https://doi.org/10.1534/genetics.110.124982
Sakudoh, Takashi ; Nakashima, Takeharu ; Kuroki, Yoko ; Fujiyama, Asao ; Kohara, Yuji ; Honda, Naoko ; Fujimoto, Hirofumi ; Shimada, Toru ; Nakagaki, Masao ; Banno, Yutaka ; Tsuchida, Kozo. / Diversity in copy number and structure of a silkworm morphogenetic gene as a result of domestication. :: Genetics. 2011 ; 巻 187, 番号 3. pp. 965-976.
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abstract = "The carotenoid-binding protein (CBP) of the domesticated silkworm, Bombyx mori, a major determinant of cocoon color, is likely to have been substantially influenced by domestication of this species. We analyzed the structure of the CBP gene in multiple strains of B. mori, in multiple individuals of the wild silkworm, B. mandarina (the putative wild ancestor of B. mori), and in a number of other lepidopterans. We found the CBP gene copy number in genomic DNA to vary widely among B. mori strains, ranging from 1 to 20. The copies of CBP are of several types, based on the presence of a retrotransposon or partial deletion of the coding sequence. In contrast to B. mori, B. mandarina was found to possess a single copy of CBP without the retrotransposon insertion, regardless of habitat. Several other lepidopterans were found to contain sequences homologous to CBP, revealing that this gene is evolutionarily conserved in the lepidopteran lineage. Thus, domestication can generate significant diversity of gene copy number and structure over a relatively short evolutionary time.",
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