DNA ploidy is a major prognostic factor in advanced gastric carcinoma- univariate and multivariate analysis

M. Haraguchi, A. Watanabe, S. Moriguchi, D. Korenaga, Y. Maehara, T. Okamura, K. Sugimachi

研究成果: Contribution to journalArticle査読

23 被引用数 (Scopus)

抄録

DNA ploidy was determined by cytofluorometric analysis of paraffin- embedded malignant tissue from 96 Japanese patients in whom gastric carcinoma had invaded the serosa. Aneuploidy was found in gastric carcinoma tissue from 63 patients (66%). The postoperative 5-year survival rate of patients with aneuploid malignancy was significantly lower (13%) than those with diploid malignancy (36%) (p < 0.05). A multivariate analysis of various clinical and pathologic factors showed that tumor size, lymph node metastasis, vascular invasion, and DNA ploidy were significant and independent factors, which correlated with prognosis.

本文言語英語
ページ(範囲)814-819
ページ数6
ジャーナルSurgery
110
5
出版ステータス出版済み - 12 1 1991

All Science Journal Classification (ASJC) codes

  • Surgery

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