Drainage retinotomy confers risk of epiretinal membrane formation following vitrectomy for rhegmatogenous retinal detachment repair

Keijiro Ishikawa, Masato Akiyama, Kenichiro Mori, Takahito Nakama, Shoji Notomi, Shintaro Nakao, Ri-Ichiro Kohno, Atsunobu Takeda, Koh-Hei Sonoda

研究成果: Contribution to journalArticle査読

抄録

PURPOSE: To describe the factors associated with epiretinal membrane (ERM) formation in eyes treated with pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD).

DESIGN: Nation-wide, multi-center, clinical cohort study based on registry data.

METHODS: Subjects: The 2239 cases treated with PPV for RRD repair registered in the Japan-Retinal Detachment Registry between February 2016 and March 2017.

PROCEDURES: Associations of 13 baseline characteristics and eight surgical procedures with ERM formation were evaluated using univariate analysis. We conducted a propensity score-matched analysis for the significantly associated clinical factor(s).

MAIN OUTCOME MEASURES: ERM formation after six months of vitrectomy.

RESULTS: ERM had developed in 104 cases (4.6%) by six months. We found that a drainage retinotomy was significantly associated with ERM after multiple testing correction (odds ratio [OR] = 2.22, 95% confidence interval [CI] = 1.50-3.31, P < 0.001). In the propensity score-matched analysis (N = 492 in each group), we confirmed a significant difference in the incidence of ERM after six months of vitrectomy (8.3% and 2.6% in cases with and without drainage retinotomy, respectively; OR = 3.35, 95% CI 1.77-6.33; P < 0.001).

CONCLUSIONS: Eyes treated with PPV combined with drainage retinotomy are more likely to develop ERM postoperatively.

本文言語英語
ジャーナルAmerican journal of ophthalmology
DOI
出版ステータス印刷前のE-pub - 7 30 2021

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