Drop head syndrome as a rare complication in mixed connective tissue disease

Midori Akagi, Masataka Umeda, Mikiko Hashisako, Kazusato Hara, Sousuke Tsuji, Yushiro Endo, Ayuko Takatani, Toshimasa Shimizu, Shoichi Fukui, Tomohiro Koga, Shin Ya Kawashiri, Naoki Iwamoto, Takashi Igawa, Kunihiro Ichinose, Mami Tamai, Hideki Nakamura, Tomoki Origuchi, Daisuke Niino, Atsushi Kawakami

研究成果: Contribution to journalArticle査読

抄録

A 54-year-old woman developed drop head syndrome (DHS), Raynaud's phenomenon and creatine kinase (CK) elevation. She did not meet the international classification criteria of dermatomyositis/polymyositis, as we observed no muscle weakness, grasping pain or electromyography abnormality in her limbs, and antiaminoacyl tRNA synthetase (ARS) antibody was negative. Cervical magnetic resonance imaging and a muscle biopsy of the trapezius muscle revealed myositis findings as the only clinical observations in muscle. These findings, along with her anti-U1-ribonucleoprotein (RNP) antibody positivity and leukopenia, resulted in a diagnosis of mixed connective tissue disease (MCTD). Prednisolone treatment significantly improved her myositis. To our knowledge, this is the first report of DHS as the only muscle complication of MCTD.

本文言語英語
ページ(範囲)729-732
ページ数4
ジャーナルInternal Medicine
59
5
DOI
出版ステータス出版済み - 3 1 2020
外部発表はい

All Science Journal Classification (ASJC) codes

  • 内科学

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