TY - JOUR
T1 - Dynamic behavior of enzymatic system realizing two-factor model
AU - Okamoto, Masahiro
AU - Katsurayama, Atsuko
AU - Tsukiji, Michiko
AU - Aso, Yoichi
AU - Hayashi, Katsuya
PY - 1980/3/7
Y1 - 1980/3/7
N2 - It has been shown that the two-factor model, introduced by Rosen for biological automata, could be realized at a molecular level by an enzymatic conjugate system. This system was applied to several metabolic regulatory models, and the dynamic behaviors were followed by computer simulation. It was revealed that the feedback system including the two-factor realizing system as a control element can maintain the stationary value of end product at a desired level against an external perturbation.
AB - It has been shown that the two-factor model, introduced by Rosen for biological automata, could be realized at a molecular level by an enzymatic conjugate system. This system was applied to several metabolic regulatory models, and the dynamic behaviors were followed by computer simulation. It was revealed that the feedback system including the two-factor realizing system as a control element can maintain the stationary value of end product at a desired level against an external perturbation.
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U2 - 10.1016/0022-5193(80)90369-0
DO - 10.1016/0022-5193(80)90369-0
M3 - Article
C2 - 6768933
AN - SCOPUS:0018897951
VL - 83
SP - 1
EP - 16
JO - Journal of Theoretical Biology
JF - Journal of Theoretical Biology
SN - 0022-5193
IS - 1
ER -