Objects and methods: In this study, we demonstrate the morphological change in two cases of lumbosacral lipoma during the first few months of life using a three-dimensional Fourier transformation-constructive interference in a steady-state (CISS) sequence that enables high-resolution images to be obtained with excellent contrast between cerebrospinal fluid (CSF), spinal roots, and lipoma. Results: The CISS images clearly demonstrated the dynamic morphological changes such as lipoma growth observed in both cases and increased tethering effect in the case with lipomyelomeningocele. Conclusion: We have to keep in mind the potential for these morphological changes of the spinal lipoma during the first few months of life.
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