Dynamics in the folding of long DNA chain under strong flow

Takuya Saito, Takahiro Sakaue, Daiji Kaneko, Masao Washizu, Hidehiro Oana

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

1 被引用数 (Scopus)

抄録

This paper presents the study about the dynamics in the folding of long DNA under strong flow. Di- rect observation of the folding process of the tethered DNA molecule induced by adding a condensing agent is demonstrated using a microfluidic device, and this theoretical interpretation of the process is provided. From the direct observation, it is found that the fold- ing dynamics typically exhibits characteristic three stages: (i) initial rapid compaction, (ii) slowing-down, (iii) sudden speed-up. Such a notable feature pin- points a nonequilibrium flow effect and can be inter- preted by a simple theory, which takes account of the nonuniformity of the tethered chain stretched by flow.

本文言語英語
ホスト出版物のタイトル2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008, with Symposium on "COE for Education and Research of Micro-Nano Mechatronics"
ページ118-123
ページ数6
DOI
出版ステータス出版済み - 12 1 2008
イベント2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008, with Symposium on "COE for Education and Research of Micro-Nano Mechatronics", Symposium on "System Cell Engineering by Multi-scale Manipulation" - Nagoya, 日本
継続期間: 11 6 200811 9 2008

出版物シリーズ

名前2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008

その他

その他2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008, with Symposium on "COE for Education and Research of Micro-Nano Mechatronics", Symposium on "System Cell Engineering by Multi-scale Manipulation"
国/地域日本
CityNagoya
Period11/6/0811/9/08

All Science Journal Classification (ASJC) codes

  • コンピュータ ビジョンおよびパターン認識
  • 人間とコンピュータの相互作用
  • 電子工学および電気工学

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