Dynamics of 2-N-tert-butylaminoxyladenosine incorporated into oligodeoxynucleotides.

Mariko Aso, Manami Kurita, John Walter Mirc, Toshiyuki Kaneko, Yoshitaka Higuchi, Noboru Koga, Hiroshi Suemune

研究成果: ジャーナルへの寄稿記事

抄録

We synthesized oligodeoxynucleotide (ODN, 3) containing 2-N-tert-butylaminoxyladenosine (1) and studied EPR spectra of 1 and its duplexes with varied sequences. Duplex formation resulted in a broadening of spectrum and a significant decrease in peak-to-peak height and peak height ratio values. The h(+)/ho values in EPR spectra well correlated with stability of duplex which indicated ODN containing 1 has the potential to monitor DNA structure.

元の言語英語
ページ(範囲)151-152
ページ数2
ジャーナルNucleic acids symposium series (2004)
発行部数52
出版物ステータス出版済み - 2008

Fingerprint

Oligodeoxyribonucleotides
DNA

All Science Journal Classification (ASJC) codes

  • Medicine(all)

これを引用

Aso, M., Kurita, M., Mirc, J. W., Kaneko, T., Higuchi, Y., Koga, N., & Suemune, H. (2008). Dynamics of 2-N-tert-butylaminoxyladenosine incorporated into oligodeoxynucleotides. Nucleic acids symposium series (2004), (52), 151-152.

Dynamics of 2-N-tert-butylaminoxyladenosine incorporated into oligodeoxynucleotides. / Aso, Mariko; Kurita, Manami; Mirc, John Walter; Kaneko, Toshiyuki; Higuchi, Yoshitaka; Koga, Noboru; Suemune, Hiroshi.

:: Nucleic acids symposium series (2004), 番号 52, 2008, p. 151-152.

研究成果: ジャーナルへの寄稿記事

Aso, M, Kurita, M, Mirc, JW, Kaneko, T, Higuchi, Y, Koga, N & Suemune, H 2008, 'Dynamics of 2-N-tert-butylaminoxyladenosine incorporated into oligodeoxynucleotides.', Nucleic acids symposium series (2004), 番号 52, pp. 151-152.
Aso, Mariko ; Kurita, Manami ; Mirc, John Walter ; Kaneko, Toshiyuki ; Higuchi, Yoshitaka ; Koga, Noboru ; Suemune, Hiroshi. / Dynamics of 2-N-tert-butylaminoxyladenosine incorporated into oligodeoxynucleotides. :: Nucleic acids symposium series (2004). 2008 ; 番号 52. pp. 151-152.
@article{d2621205dbb04267843b14644f077c2d,
title = "Dynamics of 2-N-tert-butylaminoxyladenosine incorporated into oligodeoxynucleotides.",
abstract = "We synthesized oligodeoxynucleotide (ODN, 3) containing 2-N-tert-butylaminoxyladenosine (1) and studied EPR spectra of 1 and its duplexes with varied sequences. Duplex formation resulted in a broadening of spectrum and a significant decrease in peak-to-peak height and peak height ratio values. The h(+)/ho values in EPR spectra well correlated with stability of duplex which indicated ODN containing 1 has the potential to monitor DNA structure.",
author = "Mariko Aso and Manami Kurita and Mirc, {John Walter} and Toshiyuki Kaneko and Yoshitaka Higuchi and Noboru Koga and Hiroshi Suemune",
year = "2008",
language = "English",
pages = "151--152",
journal = "Nucleic acids symposium series (2004)",
issn = "1746-8272",
publisher = "Oxford University Press",
number = "52",

}

TY - JOUR

T1 - Dynamics of 2-N-tert-butylaminoxyladenosine incorporated into oligodeoxynucleotides.

AU - Aso, Mariko

AU - Kurita, Manami

AU - Mirc, John Walter

AU - Kaneko, Toshiyuki

AU - Higuchi, Yoshitaka

AU - Koga, Noboru

AU - Suemune, Hiroshi

PY - 2008

Y1 - 2008

N2 - We synthesized oligodeoxynucleotide (ODN, 3) containing 2-N-tert-butylaminoxyladenosine (1) and studied EPR spectra of 1 and its duplexes with varied sequences. Duplex formation resulted in a broadening of spectrum and a significant decrease in peak-to-peak height and peak height ratio values. The h(+)/ho values in EPR spectra well correlated with stability of duplex which indicated ODN containing 1 has the potential to monitor DNA structure.

AB - We synthesized oligodeoxynucleotide (ODN, 3) containing 2-N-tert-butylaminoxyladenosine (1) and studied EPR spectra of 1 and its duplexes with varied sequences. Duplex formation resulted in a broadening of spectrum and a significant decrease in peak-to-peak height and peak height ratio values. The h(+)/ho values in EPR spectra well correlated with stability of duplex which indicated ODN containing 1 has the potential to monitor DNA structure.

UR - http://www.scopus.com/inward/record.url?scp=78649395850&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78649395850&partnerID=8YFLogxK

M3 - Article

SP - 151

EP - 152

JO - Nucleic acids symposium series (2004)

JF - Nucleic acids symposium series (2004)

SN - 1746-8272

IS - 52

ER -