Effect of dose reduction on the ability of digital mammography to detect simulated microcalcifications

Mari Yakabe, Shuji Sakai, Hidetake Yabuuchi, Yoshio Matsuo, Takeshi Kamitani, Taro Setoguchi, Mayumi Cho, Masafumi Masuda, Masayuki Sasaki

研究成果: ジャーナルへの寄稿記事

9 引用 (Scopus)

抄録

The purpose of this article was to report the relationship between radiation dose and the ability of sentence digital mammography to detect microcalcifications. All images were acquired by computed radiography and an anthropomorphic breast phantom. The tube voltage and anode/filter combination used were 28 kVp and Mo/Mo. Simulated microcalcifications with an approximate diameter of 250-350 μm were positioned on the phantom. Groups of six microcalcifications were arranged in one of two patterns, a line cluster 1 cm long or a hexagonal cluster 4 mm wide. One of the six microcalcifications was removed to create a negative control. Each cluster was placed on 25 different points. Four levels of milliampere-second (mAs) values were applied: 100%, 50%, 25%, and 12.5%. Five staff radiologists participated in an observer performance test. All observers used a workstation with a 3-megapixel monochrome LCD monitor. The areas under the receiver-operating characteristics curves (AUC) were used to compare diagnostic performance among the four doses. The overall AUC scores were 0.97 with 100% mAs, 0.93 (n.s.) with 50%, 0.90 (p < 0.05) with 25%, and 0.81 (p < 0.01) with 12.5% mAs. Among the negative series, the percentage of images on which observers were able to identify the removed microcalcification point decreased from 88.8% with 100% mAs to 83.6% (n.s.) with 50%, 74.8% (p < 0.001) with 25%, and 67.2% (p < 0.001) with 12.5% mAs. A certain level of dose reduction in digital mammography may be an option.

元の言語英語
ページ(範囲)520-526
ページ数7
ジャーナルJournal of Digital Imaging
23
発行部数5
DOI
出版物ステータス出版済み - 10 1 2010

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Calcinosis
Mammography
Radiography
Liquid crystal displays
Dosimetry
Anodes
Area Under Curve
Electric potential
ROC Curve
Electrodes
Breast
Radiation

All Science Journal Classification (ASJC) codes

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Computer Science Applications

これを引用

Effect of dose reduction on the ability of digital mammography to detect simulated microcalcifications. / Yakabe, Mari; Sakai, Shuji; Yabuuchi, Hidetake; Matsuo, Yoshio; Kamitani, Takeshi; Setoguchi, Taro; Cho, Mayumi; Masuda, Masafumi; Sasaki, Masayuki.

:: Journal of Digital Imaging, 巻 23, 番号 5, 01.10.2010, p. 520-526.

研究成果: ジャーナルへの寄稿記事

Yakabe, Mari ; Sakai, Shuji ; Yabuuchi, Hidetake ; Matsuo, Yoshio ; Kamitani, Takeshi ; Setoguchi, Taro ; Cho, Mayumi ; Masuda, Masafumi ; Sasaki, Masayuki. / Effect of dose reduction on the ability of digital mammography to detect simulated microcalcifications. :: Journal of Digital Imaging. 2010 ; 巻 23, 番号 5. pp. 520-526.
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abstract = "The purpose of this article was to report the relationship between radiation dose and the ability of sentence digital mammography to detect microcalcifications. All images were acquired by computed radiography and an anthropomorphic breast phantom. The tube voltage and anode/filter combination used were 28 kVp and Mo/Mo. Simulated microcalcifications with an approximate diameter of 250-350 μm were positioned on the phantom. Groups of six microcalcifications were arranged in one of two patterns, a line cluster 1 cm long or a hexagonal cluster 4 mm wide. One of the six microcalcifications was removed to create a negative control. Each cluster was placed on 25 different points. Four levels of milliampere-second (mAs) values were applied: 100{\%}, 50{\%}, 25{\%}, and 12.5{\%}. Five staff radiologists participated in an observer performance test. All observers used a workstation with a 3-megapixel monochrome LCD monitor. The areas under the receiver-operating characteristics curves (AUC) were used to compare diagnostic performance among the four doses. The overall AUC scores were 0.97 with 100{\%} mAs, 0.93 (n.s.) with 50{\%}, 0.90 (p < 0.05) with 25{\%}, and 0.81 (p < 0.01) with 12.5{\%} mAs. Among the negative series, the percentage of images on which observers were able to identify the removed microcalcification point decreased from 88.8{\%} with 100{\%} mAs to 83.6{\%} (n.s.) with 50{\%}, 74.8{\%} (p < 0.001) with 25{\%}, and 67.2{\%} (p < 0.001) with 12.5{\%} mAs. A certain level of dose reduction in digital mammography may be an option.",
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