Effect of etoposide on a human pancreatic cancer cell line exposed to high dose X-ray irradiation

K. Mizumoto, M. Tanaka, R. Aramaki

研究成果: ジャーナルへの寄稿学術誌査読

抄録

Effects of etoposide on the cell deaths of a human pancreatic cancer cell line by exposure to high-dose X-ray irradiation were examined. Both high-dose X-ray irradiation and etoposide killed the pancreatic cancer cells by apoptosis. With 30 gray irradiation, simultaneous treatment of etoposide did not alter the percentage of cell deaths; however, 24-hr prior treatment of etoposide killed a significantly larger percentage of the cells, accompanying the accumulation to the S phase of the cell cycle. The results indicate that apoptosis of human pancreatic cancer cell line induced by high dose X-ray irradiation can be enhanced by prior treatment with etoposide.

本文言語英語
ページ(範囲)1673-1675
ページ数3
ジャーナルJapanese Journal of Cancer and Chemotherapy
23
12
出版ステータス出版済み - 1996

!!!All Science Journal Classification (ASJC) codes

  • 腫瘍学
  • 癌研究

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