Effect of Gender Difference on Clinical Outcomes after CRT

Kenji Ando, Takeshi Arita, Masahiko Goya, Takeshi Kimura, Satoshi Shizuta, Takaaki Isshiki, Masakiyo Nobuyoshi

研究成果: ジャーナルへの寄稿記事

抜粋

Background: Female is reported to be preferred CRT compared to male. However, precise effect of gender difference on clinical outcomes is not well known. Methods: We investigated 651 patients from CUBIC study and divided into two groups, 197 female (F group), 454 male (M group). Results: Mean follow up were 22+/15 months. F group was older (71 years vs. 68 years, p=0.01) and more likely to have wide QRS (155 ms vs. 148 ms, p=0.027) and non-ischemic etiology (83% vs. 62%, p<0.0001). M group was more likely to have diabetic (39% vs. 20%, p<0.0001), renal failure (32% vs. 17%, p<0.0001), AF (33% vs. 25%, p=0.036), VT/VF (19% vs. 12%, p=0.027) and larger LV (64mm vs. 60mm, p<0.0001). CRT-D were more common in M group (65% vs. 47%, p<0.0001). NYHA class (F group: 2.9 vs. M group: 2.9) and LVEF (F group: 29% vs. M group: 28%) were similar. There was no difference in NYHA class (2.0 vs. 2.2, p=ns) and responder rate (63% vs.62%, p=ns) at 6-month. The event free survival rates from combined death and heart failure hospitalization, ventricular arrhythmic events were significantly higher in F group (71 % vs.60% at 2-year, Log-rank p=0.038, 79% vs.67% at 2-year, Log-rank p=0.001, respectively). Conclusion: Female has fewer commodities and seems to have preferable clinical outcomes after CRT.

元の言語英語
ページ数1
ジャーナルjournal of arrhythmia
27
発行部数4
DOI
出版物ステータス出版済み - 1 1 2011

    フィンガープリント

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

これを引用

Ando, K., Arita, T., Goya, M., Kimura, T., Shizuta, S., Isshiki, T., & Nobuyoshi, M. (2011). Effect of Gender Difference on Clinical Outcomes after CRT. journal of arrhythmia, 27(4). https://doi.org/10.4020/jhrs.27.OP26_1