Effect of orally administered conjugated linoleic acids on behaviors and tissue fatty acid compositions in mice

T. Nakanishi, A. Ohgushi, T. Yamashita, K. Sashihara, T. Takagi, E. Dobashi, T. Kamegai, M. Kasai, T. Yoshimatsu, Mitsuhiro Furuse

研究成果: ジャーナルへの寄稿学術誌査読

7 被引用数 (Scopus)

抄録

To compare the influences of the oral administration of conjugated linoleic acids (CLA) on behaviors and fatty acid composition of some tissues with those of linoleic acid (LA) and docosahexaenoic acid (DHA), mice (8-week old) were orally administered with oils containing high levels of CLA, DHA or LA for 4 weeks (6 days per week, 0.2 ml per day). Control group was administered with saline. Behavioral tests such as locomotor activity, swinf. test, elevated plus maze test and biting test were done on the commencement of the study (0 week) and 2 and 4 weeks after treatments. No significant changes were observed in all the parameters. Oral CLA increased the liver weight and reduced the epididymal white adipose tissue weight. The ratio of arachidonic acid to total fatty acids was significantly increased by LA and decreased by CLA compared with the control, especially in the liver. Small amounts of CLA were detected in the brain of mice administered with CLA or LA groups, but not detected in mice of the control and DHA groups. The level of DHA in the brain was not altered by DHA administration. It is concluded that oral administration of CLA influenced some tissues but not behaviours of mice at least after growth.

本文言語英語
ページ(範囲)157-170
ページ数14
ジャーナルJournal of Applied Animal Research
20
2
DOI
出版ステータス出版済み - 1月 1 2001

!!!All Science Journal Classification (ASJC) codes

  • 動物科学および動物学
  • 獣医学(全般)

フィンガープリント

「Effect of orally administered conjugated linoleic acids on behaviors and tissue fatty acid compositions in mice」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル