Effect of Several Sweet Substances on the Electrical Characteristics of a Dioleyl Phosphate-millipore Membrane

Satoru Iiyama, Kiyoshi Toko, Kenshi Hayashi, Kaoru Yamafuji

研究成果: Contribution to journalArticle査読

抄録

Sweet substances (sucrose, lactose, glucose, fructose, galactose, glycerin and aspartame), excepting Na saccharin, effectively interacted with a negatively-charged lipid membrane of dioleyl phosphate (DOPH). These sweet substances decreased the membrane resistance and depolarized the membrane potential. This response differed from those to bitter, sour and salty substances. Together with the result for transient response, it is suggested that sweet substances could penetrate the lipid membrane. Mono- and disaccharides exerted their effects at a concentration corresponding to the threshold value of taste sensation in vivo. Aspartame, which is about 100-fold sweeter than sucrose, was effective at one-hundredth of this concentration. In addition, the effect of sweet substances on a positively-charged lipid membrane was studied. Changes in the membrane electrical potential and resistance were observed by employing Na saccharin, which had no effect on the DOPH membrane.

本文言語英語
ページ(範囲)675-681
ページ数7
ジャーナルAgricultural and Biological Chemistry
53
3
DOI
出版ステータス出版済み - 1989

All Science Journal Classification (ASJC) codes

  • 生化学、遺伝学、分子生物学(全般)
  • 農業および生物科学(全般)

フィンガープリント

「Effect of Several Sweet Substances on the Electrical Characteristics of a Dioleyl Phosphate-millipore Membrane」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル