Effective weekly paclitaxel administration for gastric cancer with malignant ascites--a case report

Teruyoshi Ishida, Hidehiko Shimokawa, Kouji Kawaguchi, Naohiro Nose, Tohru Ikegami, Hiroyuki Itoh, Akinori Kido, Yukiharu Sasaki, Takahiro Ezaki

研究成果: Contribution to journalArticle査読

4 被引用数 (Scopus)

抄録

We report a case in which weekly paclitaxel (TXL) administration was effective for gastric cancer with malignant ascites. TXL (80 mg/m2) was infused over 1 hour after short premedication on an outpatient basis. Administration was continued for 3 weeks followed by 1 week rest. The patient was a 49-year-old woman who suffered from non-resectable gastric cancer, staged intraoperatively as having severe lymph node metastasis and malignant ascites. As an outpatient treatment, she was first treated with 5-fluorouracil combined with high-dose Leucovorin for 4 cycles. However, she complained of abdominal fullness and ascites, and received weekly TXL administration as the second line treatment. The ascites had completely disappeared 3 months after administration. The toxic events were anemia (grade 1) and alopecia (grade 2). No major adverse effects such as hypersensitivity reaction, leukopenia or peripheral neuropathy were observed.

本文言語英語
ページ(範囲)1643-1646
ページ数4
ジャーナルGan to kagaku ryoho. Cancer & chemotherapy
29
9
出版ステータス出版済み - 9 2002
外部発表はい

All Science Journal Classification (ASJC) codes

  • 医学(全般)

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