Effectiveness of Gorei-san (TJ-17) for treatment of SSRI-induced nausea and dyspepsia: Preliminary observations

Kazuo Yamada, Gohei Yagi, Shigenobu Kanba

研究成果: Contribution to journalArticle査読

17 被引用数 (Scopus)

抄録

Selective serotonin reuptake inhibitors (SSRIs) are apt to cause gastrointestinal adverse events such as nausea and dyspepsia. Gorei-san (TJ-17), which is composed of five herbs (Alismatis rhizoma, Atractylodis lanceae rhizoma, Polyporus, Hoelen, and Cinnamomi cortex), is a Japanese herbal medicine that has been used to treat nausea, dry mouth, edema, headache, and dizziness. The authors investigated the efficacy of TJ-17 for patients who experienced nausea or dyspepsia induced by SSRIs. Twenty outpatients who experienced nausea or dyspepsia induced by SSRIs were recruited for the study. Seventeen patients were female, three were male, and patient age ranged from 21 to 74 years (49.8 ± 17.0 years). TJ-17 was added to the previous regimen. Nausea and dyspepsia disappeared completely in nine patients, decreased in four patients, decreased slightly in two patients, and did not change in five patients. No adverse events were associated with the addition of TJ-17 in any patient.

本文言語英語
ページ(範囲)112-114
ページ数3
ジャーナルClinical Neuropharmacology
26
3
DOI
出版ステータス出版済み - 5 1 2003

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Clinical Neurology
  • Pharmacology (medical)

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