Effects of a novel tungsten-impregnated rubber neck shield on the quality of cerebral images acquired using 15O-labeled gas

Kei Wagatsuma, Keiichi Oda, Kenta Miwa, Motoki Inaji, Muneyuki Sakata, Jun Toyohara, Kiichi Ishiwata, Masayuki Sasaki, Kenji Ishii

研究成果: Contribution to journalArticle査読

6 被引用数 (Scopus)

抄録

The present study aimed to validate the effects of a novel tungsten-impregnated rubber neck shield on the quality of phantom and clinical 15O-labeled gas positron emission tomography (PET) images. Images were acquired in the presence or absence of a neck shield from a cylindrical phantom containing [15O]H2O (phantom study) and from three individuals using [15O]CO2, [15O]O2 and [15O]CO gas (clinical study). Data were acquired in three-dimensional (3D) mode using a Discovery PET/CT 710. Values for cerebral blood flow, cerebral blood volume, oxygen extraction fraction, and cerebral metabolic rate of oxygen with and without the neck shield were calculated from 15O-labeled gas images. Arterial radioactivity and count characteristics were evaluated in the phantom and clinical studies. The coefficient of variance (CV) for the phantom study and the standard deviation (SD) for functional images were also analyzed. The neck shield decreased the random count rates by 25–59% in the phantom and clinical studies. The noise equivalent count rate (NECR) increased by 44–66% in the phantom and clinical studies. Random count rates and NECR in [15O]CO2 images significantly differed with and without the neck shield. The improvement in visual and physical image quality with the neck shield was not observed in the phantom and clinical studies. The novel neck shield reduced random count rate and improved NECR in a 3D PET study using 15O-labeled gas. The image quality with the neck shield was similar to that without the neck shield.

本文言語英語
ページ(範囲)422-430
ページ数9
ジャーナルRadiological physics and technology
10
4
DOI
出版ステータス出版済み - 12 1 2017

All Science Journal Classification (ASJC) codes

  • Radiation
  • Physical Therapy, Sports Therapy and Rehabilitation
  • Radiology Nuclear Medicine and imaging

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