Effects of added mannitol on the setting reaction and mechanical strength of apatite cement

Ryoji Shimogoryo, Toru Eguro, Eiichiro Kimura, Michito Maruta, Shigeki Matsuya, Kunio Ishikawa

研究成果: Contribution to journalArticle査読

8 被引用数 (Scopus)

抄録

Apatite cement containing porogen can be a useful material for the fabrication of biporous (macro- and microporous) apatite, which has gained much attention as a bone substitute material because of its large surface area and that it improves cell penetration. In the present study, the effects of added mannitol on the setting reaction and mechanical strength of apatite cement were evaluated. Apatite cements containing 0-40 wt% of mannitol were prepared and allowed to set in 0.9% saline kept at 37°C for 1-7 days. Although the diametral tensile strength (DTS) value increased with time, it decreased with the amount of added mannitol. SEM observation and XRD analysis revealed that mannitol had no inhibitory effect on the transformation reaction of apatite cement to apatite. It was thus concluded that mannitol was a good candidate for the fabrication of biporous apatite because it is biocompatible, exhibits satisfactory dissolution behavior, and that it caused no inhibitory effects on the compositional transformation to apatitic material.

本文言語英語
ページ(範囲)627-633
ページ数7
ジャーナルdental materials journal
28
5
DOI
出版ステータス出版済み - 2009
外部発表はい

All Science Journal Classification (ASJC) codes

  • セラミックおよび複合材料
  • 歯科学(全般)

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