Effects of added ZnTCP on mechanical and biological properties of apatite cement

K. Ishikawa, Y. Miyamoto, T. Toh, T. Yuasa, A. Ito, M. Nagayama, K. Suzuki

研究成果: Contribution to journalConference article査読

1 被引用数 (Scopus)

抄録

Effects of added Zn doped β-tricalcium phosphate (ZnTCP) on mechanical and biological properties of apatite cement (AC) was studied. Powder x-ray diffractometer revealed that ZnTCP shows no reactivity with AC. The mechanical strength of AC decreased increasing amounts of added ZnTCP. We observed no effect on the setting time of AC when the amount of ZnTCP was 10% or less. Proliferation of the osteoblastic cells was significantly increased on the surface of AC containing 5% ZnTCP when compared with that containing no ZnTCP. In contrast, proliferation of the cells decreased on the surface of AC containing 10% ZnTCP when compared with that free from ZnTCP; indicating cytotoxity. We concluded therefore, that addition of ZnTCP to AC might be useful to enhance the osteoconductivity of AC when release of Zn2+ can be carefully regulated.

本文言語英語
ページ(範囲)785-788
ページ数4
ジャーナルKey Engineering Materials
192-195
出版ステータス出版済み - 2001
外部発表はい
イベント13th international Symposium on Ceramics in Medicine (BIOCERAMICS) - Bologna, Italy
継続期間: 11 22 200011 26 2000

All Science Journal Classification (ASJC) codes

  • 材料科学(全般)
  • 材料力学
  • 機械工学

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