Effects of eradication of Helicobacter pylori on oral malodor and the oral environment: A single-center observational study

Nao Suzuki, Richiko Beppu, Masahiro Yoneda, Toru Takeshita, Mikari Asakawa, Yoshihisa Yamashita, Takashi Hanioka, Takao Hirofuji, Tetsuo Shinohara

研究成果: Contribution to journalArticle査読

抄録

Objective: Although a relationship between Helicobacter pylori and oral malodor has been suggested, it remains to be confirmed. One reason for this is that many studies assess oral malodor subjectively. Another reason for the uncertainty is that the reduction in oral malodor may be due to the effect of antibiotics on the oral microbiota. In this study, changes in oral malodor along with the eradication treatment of H. pylori were investigated by organoleptic test and gas chromatography. In addition, the salivary bacterial composition and clinical parameters were analyzed. Results: The organoleptic test score, hydrogen sulfide and dimethyl sulfide concentrations, and all clinical parameters except for tongue-coating score were significantly decreased at 1 week compared with baseline. Although antibiotic treatment also altered the overall composition of the salivary bacterial population, it had recovered at 7 weeks. On the date that H. pylori was determined to have been eradicated from all of the subjects (7 weeks after treatment), only the organoleptic test score was significantly lower compared with baseline. The hydrogen sulfide and dimethyl sulfide concentrations were non-significantly lower than those at baseline.

本文言語英語
論文番号406
ジャーナルBMC research notes
13
1
DOI
出版ステータス出版済み - 8 28 2020

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

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