Effects of probiotic Lactobacillus salivarius WB21 on halitosis and oral health: An open-label pilot trial

Tomoyuki Iwamoto, Nao Suzuki, Kazunari Tanabe, Toru Takeshita, Takao Hirofuji

研究成果: Contribution to journalArticle査読

64 被引用数 (Scopus)

抄録

Objective: The objective of this study was to evaluate whether oral administration of lactobacilli alters the degree of halitosis and clinical conditions associated with halitosis. Study design: Twenty patients with genuine halitosis were given 2.0 × 109 Lactobacillus salivarius WB21 and xylitol in tablet form daily. Oral malodor and clinical parameters were evaluated at the same time of day for each patient after 2 and 4 weeks. Results: All 20 patients were positive for L. salivarius DNA in their saliva at 2 weeks, although 12 patients were negative for this organism at baseline. Oral malodor parameters significantly decreased at 2 weeks in the subjects with physiologic halitosis. The scores of an organoleptic test and bleeding on probing significantly decreased at 4 weeks in the subjects with oral pathologic halitosis. Conclusions: Oral administration of probiotic lactobacilli primarily improved physiologic halitosis and also showed beneficial effects on bleeding on probing from the periodontal pocket.

本文言語英語
ページ(範囲)201-208
ページ数8
ジャーナルOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology
110
2
DOI
出版ステータス出版済み - 8 13 2010

All Science Journal Classification (ASJC) codes

  • 外科
  • 口腔外科
  • 耳鼻咽喉科学
  • 歯科学(全般)

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