Effects of sulpiride treatment on the levels of immunoreactive β-endorphin in rat hypothalamic nuclei

Akito Nohtomi, Masatoshi Itoh, Nobuo Yufu

研究成果: ジャーナルへの寄稿学術誌査読

28 被引用数 (Scopus)

抄録

The effects of sulpiride, a specific dopamine receptor antagonist, on the levels of immunoreactive β-endorphin (ir-β-END) in discrete hypothalamic nuclei of rats were investigated. Single injections of sulpiride significantly decreased the levels of ir-β-END in the nucleus arcuatus, nucleus paraventricularis and median eminence. Repeated injections of sulpiride significantly increased the levels of ir-β-END in the nucleus arcuatus, nucleus periventricularis and median eminence. These findings suggest that β-endorphinergic neurons are under dopaminergic control.

本文言語英語
ページ(範囲)152-156
ページ数5
ジャーナルBrain Research
300
1
DOI
出版ステータス出版済み - 5月 21 1984
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 神経科学(全般)
  • 分子生物学
  • 発生生物学
  • 臨床神経学

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