Effects of the carbonate content in carbonate apatite on bone replacement

研究成果: ジャーナルへの寄稿学術誌査読

1 被引用数 (Scopus)

抄録

Carbonate apatite (CO3Ap), an inorganic component of human bone, has been clinically applied as an artificial bone substitute. In this study, the effects of the CO3 content in CO3Ap on the replacement by new bone were studied by fabricating CO3Ap granules containing 0.9–8.3 wt% of CO3. The dissolution rate of CO3Ap in a weak acidic solution, mimicking the Howship's lacunae, was rapid for the CO3Ap granules containing a larger amount of CO3. Histological analyses demonstrated the rapid resorption in CO3Ap and replacement by natural bone tissue when the CO3 content was increased. Therefore, the CO3 content in CO3Ap is a key factor that influences the replacement of the bone tissue.

本文言語英語
ページ(範囲)200-206
ページ数7
ジャーナルJournal of Tissue Engineering and Regenerative Medicine
16
2
DOI
出版ステータス出版済み - 2月 2022

!!!All Science Journal Classification (ASJC) codes

  • 医学(その他)
  • 生体材料
  • 生体医工学

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