Effort-reward imbalance, overcommitment, and cellular immune measures among white-collar employees

Akinori Nakata, Masaya Takahashi, Masahiro Irie

    研究成果: ジャーナルへの寄稿学術誌査読

    22 被引用数 (Scopus)


    We investigated whether chronic job stress, i.e., effort-reward imbalance (ERI) and overcommitment is associated with cellular immunity among 190 male and 157 female white-collar daytime employees (mean age 38; range 22-69 years). Participants provided a blood sample for the measurement of circulating immune (natural killer (NK), B, and T) cell counts and NK cell cytotoxicity (NKCC) and completed a questionnaire survey during April to June 2002. Stepwise multiple linear regression analyses revealed that NK cells were associated with effort (β= -230; p= .013), reward (β= .169; p= .047), and ERI (β= -182; p= .047) scores but not with overcommitment in men; reward score was positively associated with NKCC (β= .167; p= .049) and inversely associated with B cells (β= -181; p= .030). No significant associations were found in women. Although the picture remains less clear in women, our findings suggest a potential immunological pathway linking adverse working conditions and stress-related disorders in men.

    ジャーナルBiological Psychology
    出版ステータス出版済み - 12月 2011

    !!!All Science Journal Classification (ASJC) codes

    • 神経科学(全般)
    • 神経心理学および生理心理学


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