EGFR gets in the way of microRNA biogenesis

Naohiro Nishida, Koshi Mimori, Masaki Mori, George A. Calin

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)

抜粋

Recent studies suggest that microRNA (miRNA) processing is a key regulatory step in the miRNA biogenesis as well as its transcriptional control. In a paper recently published in Nature, Shen et al. revealed that epidermal growth factor receptor (EGFR) directly interacts with argonaute 2 (AGO2), a critical component of RNA-induced silencing complex (RISC), and inhibits the maturation of specific tumor suppressive miRNAs under hypoxic condition.

元の言語英語
ページ(範囲)1157-1158
ページ数2
ジャーナルCell Research
23
発行部数10
DOI
出版物ステータス出版済み - 10 1 2013

    フィンガープリント

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Cell Biology

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