Electric oscillation in an excitable model membrane impregnated with lipid analogues

Satoru Iiyama, Kiyoshi Toko, Kaoru Yamafuji

研究成果: Contribution to journalArticle査読

17 被引用数 (Scopus)

抄録

A model membrane constructed from a Millipore filter, whose pores were impregnated with dioleyl phosphate, exhibited an electric self-oscillation under nonequilibrium conditions. The membrane interposed between two solutions with the same KCl concentrations showed no temporal change in membrane potential. However, the potential became oscillatory on application of an electric current to the membrane. The frequency was proportional to the magnitude of the electric current. When both KCl solutions were replaced by NaCl solutions, a similar trend was observed, although the oscillation was not as regular as in the case of KCl. A membrane placed between equimolar solutions of KCl and NaCl, on the other hand, gave rise to an oscillation even without current application. When a membrane was placed between 5 mM KCl and 100 mM KCl, it was found that NaCl added to the 5 mM KCl side had a pronounced effect on the membrane with respect to the frequency response of the oscillation. These results indicate that the dioleyl phosphate membrane discriminates Na+ from K+.

本文言語英語
ページ(範囲)129-135
ページ数7
ジャーナルBiophysical Chemistry
28
2
DOI
出版ステータス出版済み - 1 1 1987

All Science Journal Classification (ASJC) codes

  • 生物理学
  • 生化学
  • 有機化学

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